Telomestatin
95%
- Product Code: 124864
CAS:
265114-54-3
| Molecular Weight: | 582.5 g./mol | Molecular Formula: | C₂₆H₁₄N₈O₇S |
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| Density: | Storage Condition: | -20°C, sealed, dry |
Product Description:
Telomestatin is primarily recognized for its role in inhibiting telomerase activity, an enzyme crucial for the maintenance of telomeres in cancer cells. By targeting and destabilizing G-quadruplex structures in telomeric DNA, it effectively prevents telomerase from elongating telomeres, leading to cellular senescence or apoptosis in cancer cells. This mechanism makes it a promising candidate for anticancer therapies, particularly in cancers that rely on telomerase for unlimited proliferation. Additionally, telomestatin has been studied for its potential in aging research, as telomere shortening is associated with cellular aging. Its ability to modulate telomere dynamics also opens avenues for exploring its use in treating age-related diseases. Research continues to explore its efficacy and safety in clinical applications.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
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| 0.001 | 10-20 days | $2,596.50 |
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| 0.005 | 10-20 days | $12,950.37 |
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Telomestatin
Telomestatin is primarily recognized for its role in inhibiting telomerase activity, an enzyme crucial for the maintenance of telomeres in cancer cells. By targeting and destabilizing G-quadruplex structures in telomeric DNA, it effectively prevents telomerase from elongating telomeres, leading to cellular senescence or apoptosis in cancer cells. This mechanism makes it a promising candidate for anticancer therapies, particularly in cancers that rely on telomerase for unlimited proliferation. Additionally, telomestatin has been studied for its potential in aging research, as telomere shortening is associated with cellular aging. Its ability to modulate telomere dynamics also opens avenues for exploring its use in treating age-related diseases. Research continues to explore its efficacy and safety in clinical applications.
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