N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine
98%
- Product Code: 126934
Alias:
N2-isobutyryl-5'-O-(4,4'-dimethoxytriphenyl)-2'-deoxyguanosine
CAS:
68892-41-1
| Molecular Weight: | 639.7 g./mol | Molecular Formula: | C₃₅H₃₇N₅O₇ |
|---|---|---|---|
| EC Number: | 272-615-4 | MDL Number: | MFCD00010059 |
| Melting Point: | ~150 °C (dec.)(lit.) | Boiling Point: | |
| Density: | Storage Condition: | -20°C |
Product Description:
This chemical is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. It serves as a protected deoxyguanosine derivative, where the isobutyryl group protects the exocyclic amine, and the dimethoxytrityl (DMT) group protects the 5'-hydroxyl during solid-phase oligonucleotide synthesis. This protection ensures selective coupling reactions and prevents unwanted side reactions. The compound is essential in the automated synthesis of DNA sequences, enabling the creation of probes, primers, and other nucleic acid-based tools for applications such as PCR, gene editing, and sequencing. Its role in maintaining the integrity and specificity of nucleotide assembly makes it a critical component in biotechnology and pharmaceutical development.
Product Specification:
| Test | Specification |
|---|---|
| Purity (HPLC) | 97.5-100 |
| Specific Rotation | 8 Degree Celsius-9.5 Degree Celsius |
| Water | 0-1 |
| WATER | 0 1% |
| Appearance | White Powder Or Solid |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | $13.83 |
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| 5.000 | 10-20 days | $66.16 |
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| 10.000 | 10-20 days | $131.19 |
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| 25.000 | 10-20 days | $272.10 |
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N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine
This chemical is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. It serves as a protected deoxyguanosine derivative, where the isobutyryl group protects the exocyclic amine, and the dimethoxytrityl (DMT) group protects the 5'-hydroxyl during solid-phase oligonucleotide synthesis. This protection ensures selective coupling reactions and prevents unwanted side reactions. The compound is essential in the automated synthesis of DNA sequences, enabling the creation of probes, primers, and other nucleic acid-based tools for applications such as PCR, gene editing, and sequencing. Its role in maintaining the integrity and specificity of nucleotide assembly makes it a critical component in biotechnology and pharmaceutical development.
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