tert-Butyl(((3aR,4R,6aR)-5-fluoro-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane
≥95%
- Product Code: 36054
CAS:
805245-41-4
| Molecular Weight: | 684.91 g./mol | Molecular Formula: | C₄₄H₄₅FO₄Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD25977137 | |
| Melting Point: | Boiling Point: | 681.5°C at 760 mmHg | |
| Density: | Storage Condition: | 2-8°C, dry and sealed |
Product Description:
This chemical is primarily used in organic synthesis, particularly in the protection of hydroxyl groups during complex multi-step reactions. Its structure, featuring a diphenylsilane group, makes it highly effective for temporary protection of sensitive functional groups, especially in the synthesis of nucleosides and nucleotides. The tert-butyl group provides steric hindrance, enhancing stability and selectivity during reactions. It is commonly employed in the preparation of fluorinated cyclopentane derivatives, which are key intermediates in the development of antiviral and anticancer drugs. The trityl group further aids in selective deprotection, allowing for precise control over reaction pathways. This compound is particularly valuable in medicinal chemistry for constructing complex molecular architectures with high precision.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to off-white solid |
| PURITY | 94.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $267.70 |
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| 0.250 | 10-20 days | $487.19 |
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tert-Butyl(((3aR,4R,6aR)-5-fluoro-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane
This chemical is primarily used in organic synthesis, particularly in the protection of hydroxyl groups during complex multi-step reactions. Its structure, featuring a diphenylsilane group, makes it highly effective for temporary protection of sensitive functional groups, especially in the synthesis of nucleosides and nucleotides. The tert-butyl group provides steric hindrance, enhancing stability and selectivity during reactions. It is commonly employed in the preparation of fluorinated cyclopentane derivatives, which are key intermediates in the development of antiviral and anticancer drugs. The trityl group further aids in selective deprotection, allowing for precise control over reaction pathways. This compound is particularly valuable in medicinal chemistry for constructing complex molecular architectures with high precision.
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