(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol

98%

  • Product Code: 36481
  CAS:    20227-41-2
Molecular Weight: 269.23 g./mol Molecular Formula: C₁₀H₁₂FN₅O₃
EC Number: MDL Number: MFCD12911815
Melting Point: Boiling Point: 628.644°C at 760 mmHg
Density: Storage Condition: 2-8°C, protected from light, stored in an inert gas
Product Description: This compound is primarily utilized in the field of medicinal chemistry and drug development. It serves as a modified nucleoside, often incorporated into oligonucleotides for research purposes, particularly in studying RNA structure and function. The fluorine substitution enhances its stability and resistance to enzymatic degradation, making it valuable in the development of antisense oligonucleotides and siRNAs for therapeutic applications. Additionally, it is explored in the design of antiviral and anticancer agents, where its unique structure can interfere with viral replication or cancer cell proliferation. Its role in probing biochemical pathways and as a potential therapeutic agent highlights its significance in biomedical research.
Product Specification:
Test Specification
APPEARANCE White to off-white Solid
PURITY 97.5-100
Infrared spectrum Conforms to Structure
NMR Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.100 10-20 days $352.17
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0.250 10-20 days $654.08
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1.000 10-20 days $1,964.11
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(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
This compound is primarily utilized in the field of medicinal chemistry and drug development. It serves as a modified nucleoside, often incorporated into oligonucleotides for research purposes, particularly in studying RNA structure and function. The fluorine substitution enhances its stability and resistance to enzymatic degradation, making it valuable in the development of antisense oligonucleotides and siRNAs for therapeutic applications. Additionally, it is explored in the design of antiviral and anticancer agents, where its unique structure can interfere with viral replication or cancer cell proliferation. Its role in probing biochemical pathways and as a potential therapeutic agent highlights its significance in biomedical research.
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