(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)-ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
99%, simple miscellaneous 0.2%, ee99.5%
- Product Code: 36486
CAS:
171482-05-6
| Molecular Weight: | 473.82 g./mol | Molecular Formula: | C₂₀H₁₉ClF₇NO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD13183776 | |
| Melting Point: | Boiling Point: | 387.9°C | |
| Density: | Storage Condition: | room temperature, dry |
Product Description:
This compound is primarily utilized in the pharmaceutical industry as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders. Its structural features, including the morpholine ring and trifluoromethyl groups, contribute to its role in enhancing drug potency and selectivity. It is often employed in the development of neurokinin-1 (NK1) receptor antagonists, which are used to treat conditions such as chemotherapy-induced nausea and vomiting, as well as certain psychiatric disorders. Additionally, its chiral centers make it valuable in the production of enantiomerically pure drugs, ensuring higher efficacy and reduced side effects.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White powder |
| PURITY | 98.5-100 |
| Infrared spectrum | Conforms to Structure |
| Single miscellaneous | 0.2 |
| ee | 99.45 100% |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | $88.29 |
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| 5.000 | 10-20 days | $241.86 |
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| 25.000 | 10-20 days | $730.76 |
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(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)-ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
This compound is primarily utilized in the pharmaceutical industry as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders. Its structural features, including the morpholine ring and trifluoromethyl groups, contribute to its role in enhancing drug potency and selectivity. It is often employed in the development of neurokinin-1 (NK1) receptor antagonists, which are used to treat conditions such as chemotherapy-induced nausea and vomiting, as well as certain psychiatric disorders. Additionally, its chiral centers make it valuable in the production of enantiomerically pure drugs, ensuring higher efficacy and reduced side effects.
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