Guanidine Thiocyanate
99% Biotech Grade
- Product Code: 51824
| Molecular Weight: | 118.16 g./mol | Molecular Formula: | C₂H₆N₄S |
|---|---|---|---|
| EC Number: | 209-812-1 | MDL Number: | MFCD00013027 |
| Melting Point: | 120-122 °C(lit.) | Boiling Point: | |
| Density: | 1.103 g/mL at 20 °C | Storage Condition: | room temperature |
Guanidine thiocyanate is widely used in molecular biology for the isolation of nucleic acids, particularly RNA, due to its ability to denature proteins and inhibit RNases. It is a key component in many RNA extraction protocols, ensuring the integrity of RNA samples by preventing degradation. Additionally, it is employed in the preparation of DNA and RNA for various downstream applications, such as PCR, sequencing, and hybridization. Its chaotropic properties make it effective in disrupting cell membranes and releasing nucleic acids, making it indispensable in genetic research and diagnostics.
| Test | Specification |
|---|---|
| Purity | 99%-100% |
| Melting point | 115°C-121°C |
| Chloride (Cl-) | 0-0.05% |
| Total Metallic Impurities | 0ppm-300ppm |
| Appearance | White to Almost white powder to crystal |
| DNAses | None detected |
| RNAses | None detected |
| Proteases | None detected |
| Phosphatases | None detected |
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 25.000 | 10-20 days | £11.08 |
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| 100.000 | 10-20 days | £22.39 |
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| 250.000 | 10-20 days | £54.28 |
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| 500.000 | 10-20 days | £100.87 |
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| 2500.000 | 10-20 days | £356.67 |
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| 10000.000 | 10-20 days | £1,354.76 |
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Guanidine thiocyanate is widely used in molecular biology for the isolation of nucleic acids, particularly RNA, due to its ability to denature proteins and inhibit RNases. It is a key component in many RNA extraction protocols, ensuring the integrity of RNA samples by preventing degradation. Additionally, it is employed in the preparation of DNA and RNA for various downstream applications, such as PCR, sequencing, and hybridization. Its chaotropic properties make it effective in disrupting cell membranes and releasing nucleic acids, making it indispensable in genetic research and diagnostics.
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