6-azauridine 6-Azauracil

99% biotech grade

  • Product Code: 52722
  CAS:    461-89-2
Molecular Weight: 113.07 g./mol Molecular Formula: C₃H₃N₃O₂
EC Number: 207-318-0 MDL Number: MFCD00006456
Melting Point: 274-275 °C(lit.) Boiling Point:
Density: Storage Condition: room temperature
Product Description: 6-Azauridine, a derivative of 6-azauracil, is primarily utilized in the field of medical research and therapy due to its ability to interfere with nucleic acid synthesis. It acts as an antimetabolite, inhibiting the enzymatic conversion of orotic acid to uridine monophosphate, which is a crucial step in the biosynthesis of pyrimidine nucleotides. This property makes it effective in the treatment of certain types of cancer, as it can selectively target and inhibit the proliferation of rapidly dividing cancer cells. Additionally, it has been explored for its antiviral properties, particularly against RNA viruses, by disrupting viral replication processes. In research settings, 6-azauridine is used to study the mechanisms of nucleotide metabolism and to develop novel therapeutic strategies for diseases involving abnormal cell growth.
Product Specification:
Test Specification
PURITY 98.5-100
PURITYNEUTRALIZATION TITRATION 98.5-101.5
APPEARANCE White to yellow powder
INFRARED SPECTRUM Conforms to Structure
SOLUBILITY IN 1M NH4OH COLORLESS TO YELLOW-GREEN,CLEAR TO HAZY,50 MG/ML
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
1.000 10-20 days $25.96
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5.000 10-20 days $54.27
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25.000 10-20 days $195.84
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100.000 10-20 days $660.68
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6-azauridine 6-Azauracil
6-Azauridine, a derivative of 6-azauracil, is primarily utilized in the field of medical research and therapy due to its ability to interfere with nucleic acid synthesis. It acts as an antimetabolite, inhibiting the enzymatic conversion of orotic acid to uridine monophosphate, which is a crucial step in the biosynthesis of pyrimidine nucleotides. This property makes it effective in the treatment of certain types of cancer, as it can selectively target and inhibit the proliferation of rapidly dividing cancer cells. Additionally, it has been explored for its antiviral properties, particularly against RNA viruses, by disrupting viral replication processes. In research settings, 6-azauridine is used to study the mechanisms of nucleotide metabolism and to develop novel therapeutic strategies for diseases involving abnormal cell growth.
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