Propargyl-PEG8-NHS ester
97%
- Product Code: 55966
CAS:
2182601-74-5
| Molecular Weight: | 533.57 g./mol | Molecular Formula: | C₂₄H₃₉NO₁₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD31536764 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry, sealed |
Product Description:
Propargyl-PEG8-NHS ester is widely used in bioconjugation and chemical biology for attaching biomolecules to various substrates. Its NHS ester group reacts efficiently with primary amines, enabling the labeling of proteins, peptides, and antibodies. The propargyl group allows for further functionalization via click chemistry, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), making it a versatile linker in the synthesis of complex molecular architectures. This compound is particularly valuable in the development of drug delivery systems, where it facilitates the attachment of targeting ligands or therapeutic agents to polymers or nanoparticles. Additionally, it is employed in the preparation of bioconjugates for diagnostic applications, such as fluorescent probes or imaging agents, enhancing specificity and detection efficiency. Its PEG spacer improves solubility and reduces immunogenicity, making it suitable for in vivo applications.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | €617.34 |
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Propargyl-PEG8-NHS ester
Propargyl-PEG8-NHS ester is widely used in bioconjugation and chemical biology for attaching biomolecules to various substrates. Its NHS ester group reacts efficiently with primary amines, enabling the labeling of proteins, peptides, and antibodies. The propargyl group allows for further functionalization via click chemistry, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), making it a versatile linker in the synthesis of complex molecular architectures. This compound is particularly valuable in the development of drug delivery systems, where it facilitates the attachment of targeting ligands or therapeutic agents to polymers or nanoparticles. Additionally, it is employed in the preparation of bioconjugates for diagnostic applications, such as fluorescent probes or imaging agents, enhancing specificity and detection efficiency. Its PEG spacer improves solubility and reduces immunogenicity, making it suitable for in vivo applications.
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