4-Chloro-2-(4-fluorophenyl)pyrimidine-5-boronic acid

95%

  • Product Code: 60892
  CAS:    2225174-28-5
Molecular Weight: 252.4371832 g./mol Molecular Formula: C₁₀H₇BClFN₂O₂
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Density: Storage Condition: -20°C, sealed, dry
Product Description: 4-Chloro-2-(4-fluorophenyl)pyrimidine-5-boronic acid is primarily used in organic synthesis, particularly in cross-coupling reactions such as the Suzuki-Miyaura reaction. This reaction is widely employed in the pharmaceutical industry to construct complex molecules, including active pharmaceutical ingredients (APIs). The boronic acid group in the compound facilitates the formation of carbon-carbon bonds, making it a valuable building block for creating diverse heterocyclic compounds. Its pyrimidine core is often utilized in the development of drugs targeting various diseases, including cancer and infectious diseases, due to its ability to interact with biological targets. Additionally, the presence of both chloro and fluoro substituents enhances its reactivity and selectivity in synthetic processes, making it a versatile intermediate in medicinal chemistry and drug discovery.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days $288.39
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0.025 10-20 days $648.06
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4-Chloro-2-(4-fluorophenyl)pyrimidine-5-boronic acid
4-Chloro-2-(4-fluorophenyl)pyrimidine-5-boronic acid is primarily used in organic synthesis, particularly in cross-coupling reactions such as the Suzuki-Miyaura reaction. This reaction is widely employed in the pharmaceutical industry to construct complex molecules, including active pharmaceutical ingredients (APIs). The boronic acid group in the compound facilitates the formation of carbon-carbon bonds, making it a valuable building block for creating diverse heterocyclic compounds. Its pyrimidine core is often utilized in the development of drugs targeting various diseases, including cancer and infectious diseases, due to its ability to interact with biological targets. Additionally, the presence of both chloro and fluoro substituents enhances its reactivity and selectivity in synthetic processes, making it a versatile intermediate in medicinal chemistry and drug discovery.
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