GSK923295
95%
- Product Code: 62695
CAS:
1088965-37-0
| Molecular Weight: | 592.13 g./mol | Molecular Formula: | C₃₂H₃₈ClN₅O₄ |
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| EC Number: | MDL Number: | MFCD16038931 | |
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| Density: | Storage Condition: | -20℃ |
Product Description:
GSK923295 is primarily utilized in cancer research due to its role as a potent and selective inhibitor of centromere-associated protein E (CENP-E), a kinesin motor protein. This compound is particularly significant in studying the mechanisms of cell division, specifically during mitosis, where CENP-E plays a crucial role in chromosome alignment and segregation. By inhibiting CENP-E, GSK923295 induces mitotic arrest, leading to cell death in rapidly dividing cancer cells. Its application is valuable in preclinical studies to understand tumor biology and evaluate potential therapeutic strategies for targeting mitosis in cancer treatment. Additionally, it serves as a tool compound in molecular biology to explore the functional roles of CENP-E in cellular processes.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | $398.80 |
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GSK923295
GSK923295 is primarily utilized in cancer research due to its role as a potent and selective inhibitor of centromere-associated protein E (CENP-E), a kinesin motor protein. This compound is particularly significant in studying the mechanisms of cell division, specifically during mitosis, where CENP-E plays a crucial role in chromosome alignment and segregation. By inhibiting CENP-E, GSK923295 induces mitotic arrest, leading to cell death in rapidly dividing cancer cells. Its application is valuable in preclinical studies to understand tumor biology and evaluate potential therapeutic strategies for targeting mitosis in cancer treatment. Additionally, it serves as a tool compound in molecular biology to explore the functional roles of CENP-E in cellular processes.
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