N-(Trimethylsilyl)acetamide

95%

  • Product Code: 63743
  Alias:    N-(Trimethylsilyl)acetamide
  CAS:    13435-12-6
Molecular Weight: 131.25 g./mol Molecular Formula: C₅H₁₃NOSi
EC Number: 236-565-7 MDL Number: MFCD00008671
Melting Point: 39-43 °C(lit.) Boiling Point: 104-106°C 35mm Hg(lit.)
Density: 0.898 g/mL at 25 °C(lit.) Storage Condition: 2~8℃, combustible area
Product Description: N-(Trimethylsilyl)acetamide is primarily used as a silylating agent in organic synthesis. It is effective in introducing the trimethylsilyl group to various organic compounds, particularly in the protection of hydroxyl and amino groups during complex chemical reactions. This compound is valuable in the preparation of silyl ethers and silyl amines, which are intermediates in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it is utilized in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing the volatility and stability of analytes for accurate detection and analysis. Its role in facilitating selective reactions and improving the efficiency of synthetic processes makes it a crucial reagent in modern chemical research and industrial applications.
Product Specification:
Test Specification
PURITY NMR 94.5-100
APPEARANCE WHITE TO LIGHT YELLOW TO YELLOW CRYSTALS OR SOLID
INFRARED SPECTROMETRY Conforms to Structure
NOTE: This product is low melting point solid,may change state in different environments (solid, liquid or semi-solid)
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
5.000 10-20 days £28.50
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25.000 10-20 days £85.94
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100.000 10-20 days £309.63
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N-(Trimethylsilyl)acetamide
N-(Trimethylsilyl)acetamide is primarily used as a silylating agent in organic synthesis. It is effective in introducing the trimethylsilyl group to various organic compounds, particularly in the protection of hydroxyl and amino groups during complex chemical reactions. This compound is valuable in the preparation of silyl ethers and silyl amines, which are intermediates in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it is utilized in the derivatization of compounds for gas chromatography and mass spectrometry, enhancing the volatility and stability of analytes for accurate detection and analysis. Its role in facilitating selective reactions and improving the efficiency of synthetic processes makes it a crucial reagent in modern chemical research and industrial applications.
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