(R)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid
95%
- Product Code: 67178
CAS:
137862-87-4
| Molecular Weight: | 435.53 g./mol | Molecular Formula: | C₂₄H₂₉N₆O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD18252868 | |
| Melting Point: | 108-110 °C (lit.) | Boiling Point: | |
| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used primarily in the pharmaceutical industry, this compound is a key intermediate in the synthesis of angiotensin II receptor antagonists, which are critical for managing hypertension and related cardiovascular conditions. Its structure is designed to effectively block the action of angiotensin II, a hormone that constricts blood vessels and increases blood pressure. This makes it valuable in the development of drugs aimed at reducing blood pressure and preventing complications such as heart attacks and strokes. Additionally, its specific stereochemistry enhances its binding affinity to the target receptor, improving the efficacy of the final drug product.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to Off-White Solid |
| PURITY | 94.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | €499.41 |
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| 0.500 | 10-20 days | €1,318.04 |
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(R)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid
Used primarily in the pharmaceutical industry, this compound is a key intermediate in the synthesis of angiotensin II receptor antagonists, which are critical for managing hypertension and related cardiovascular conditions. Its structure is designed to effectively block the action of angiotensin II, a hormone that constricts blood vessels and increases blood pressure. This makes it valuable in the development of drugs aimed at reducing blood pressure and preventing complications such as heart attacks and strokes. Additionally, its specific stereochemistry enhances its binding affinity to the target receptor, improving the efficacy of the final drug product.
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