()-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)

99%

  • Product Code: 68610
  Alias:    (2S,3S)-(+)-1,4-bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol
  CAS:    37002-48-5
Molecular Weight: 498.53 g./mol Molecular Formula: C₃₁H₃₂O₂P₂
EC Number: MDL Number: MFCD00009760
Melting Point: 86-88 °C(lit.) Boiling Point:
Density: Storage Condition: 2~8°C, dry, sealed
Product Description: This chemical is primarily utilized as a chiral ligand in asymmetric synthesis, particularly in transition metal-catalyzed reactions. Its structure, featuring diphenylphosphino groups, makes it highly effective in coordinating with metals like rhodium, iridium, and palladium, enabling the formation of enantioselective catalysts. These catalysts are widely employed in the production of pharmaceuticals and fine chemicals, where achieving high enantiomeric purity is critical. Additionally, its isopropylidene-protected dihydroxy moiety enhances stability and reactivity, making it suitable for use in complex organic transformations such as hydrogenation, hydroformylation, and cross-coupling reactions. Its application is especially valuable in the synthesis of chiral intermediates for drugs and bioactive molecules.
Product Specification:
Test Specification
PURITY 98.5-100
SPECIFIC ROTATION A20DC2 CHCL3 25 27
APPEARANCE WHITE TO LIGHT YELLOW POWDER
INFRARED SPECTRUM Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.250 10-20 days $76.81
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-
1.000 10-20 days $286.53
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()-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)
This chemical is primarily utilized as a chiral ligand in asymmetric synthesis, particularly in transition metal-catalyzed reactions. Its structure, featuring diphenylphosphino groups, makes it highly effective in coordinating with metals like rhodium, iridium, and palladium, enabling the formation of enantioselective catalysts. These catalysts are widely employed in the production of pharmaceuticals and fine chemicals, where achieving high enantiomeric purity is critical. Additionally, its isopropylidene-protected dihydroxy moiety enhances stability and reactivity, making it suitable for use in complex organic transformations such as hydrogenation, hydroformylation, and cross-coupling reactions. Its application is especially valuable in the synthesis of chiral intermediates for drugs and bioactive molecules.
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