Nα-(2,4,6-Triisopropylbenzenesulfonyl)-O-(tert-butyldiphenylsilyl)-π-methyl-L-histidinol
98%
- Product Code: 71260
CAS:
787554-04-5
Molecular Weight: | 660.01 g./mol | Molecular Formula: | C₃₈H₅₃N₃O₃SSi |
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EC Number: | MDL Number: | ||
Melting Point: | 177 °C | Boiling Point: | |
Density: | Storage Condition: | room temperature |
Product Description:
This chemical is primarily utilized in peptide synthesis as a protecting group for histidine residues. It helps to prevent unwanted side reactions during the coupling of amino acids, ensuring the accuracy and efficiency of peptide chain assembly. The tert-butyldiphenylsilyl group protects the hydroxyl moiety, while the triisopropylbenzenesulfonyl group shields the imidazole ring of histidine. This dual protection is particularly useful in complex peptide synthesis, where selective deprotection can be achieved without disrupting the overall structure. Its application is crucial in the production of bioactive peptides, pharmaceuticals, and research compounds where precise control over peptide assembly is required.
Product Specification:
Test | Specification |
---|---|
Melting point | 171 177? |
PURITYHPLC | 98 100% |
PURITYWITH TOTAL NITROGEN | 98 100% |
SPECIFIC ROTATION A20DC1 CHCL3 | 4 6 |
INFRARED SPECTROMETRY | Conforms to Structure |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.100 | 10-20 days | $450.95 |
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Nα-(2,4,6-Triisopropylbenzenesulfonyl)-O-(tert-butyldiphenylsilyl)-π-methyl-L-histidinol
This chemical is primarily utilized in peptide synthesis as a protecting group for histidine residues. It helps to prevent unwanted side reactions during the coupling of amino acids, ensuring the accuracy and efficiency of peptide chain assembly. The tert-butyldiphenylsilyl group protects the hydroxyl moiety, while the triisopropylbenzenesulfonyl group shields the imidazole ring of histidine. This dual protection is particularly useful in complex peptide synthesis, where selective deprotection can be achieved without disrupting the overall structure. Its application is crucial in the production of bioactive peptides, pharmaceuticals, and research compounds where precise control over peptide assembly is required.
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