6-Maleimidocaproic acid
98%
- Product Code: 73803
Alias:
N-maleimidocaproic acid; N-(5-carboxypentyl)maleimide
CAS:
55750-53-3
| Molecular Weight: | 211.21 g./mol | Molecular Formula: | C₁₀H₁₃NO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | 86-91 °C | Boiling Point: | |
| Density: | Storage Condition: | 2~8°C |
Product Description:
6-Maleimidocaproic acid is widely used in bioconjugation chemistry, particularly for linking biomolecules such as proteins, peptides, and antibodies. Its maleimide group reacts selectively with thiol groups (-SH) under mild conditions, making it valuable for creating stable thioether bonds. This property is especially useful in the development of antibody-drug conjugates (ADCs), where it helps attach cytotoxic drugs to antibodies for targeted cancer therapy. Additionally, it is employed in the modification of surfaces for biosensors and in the preparation of cross-linked polymers for drug delivery systems. Its spacer arm provides flexibility, ensuring optimal orientation and functionality of conjugated molecules.
Product Specification:
| Test | Specification |
|---|---|
| Purity | 97 100% |
| Melting point | 86 91? |
| Appearance | White or off-white powder |
| Identification | NMR conform |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | $19.26 |
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| 5.000 | 10-20 days | $43.21 |
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| 25.000 | 10-20 days | $162.03 |
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| 100.000 | 10-20 days | $539.15 |
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6-Maleimidocaproic acid
6-Maleimidocaproic acid is widely used in bioconjugation chemistry, particularly for linking biomolecules such as proteins, peptides, and antibodies. Its maleimide group reacts selectively with thiol groups (-SH) under mild conditions, making it valuable for creating stable thioether bonds. This property is especially useful in the development of antibody-drug conjugates (ADCs), where it helps attach cytotoxic drugs to antibodies for targeted cancer therapy. Additionally, it is employed in the modification of surfaces for biosensors and in the preparation of cross-linked polymers for drug delivery systems. Its spacer arm provides flexibility, ensuring optimal orientation and functionality of conjugated molecules.
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