N-Boc-PEG5-alcohol
97%
- Product Code: 76703
CAS:
1404111-67-6
Molecular Weight: | 337.41 g./mol | Molecular Formula: | C₁₅H₃₁NO₇ |
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EC Number: | MDL Number: | ||
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | -20°C |
Product Description:
N-Boc-PEG5-alcohol is widely used in organic synthesis and bioconjugation due to its unique properties. Its PEG (polyethylene glycol) spacer provides solubility and flexibility, making it valuable for modifying biomolecules like peptides, proteins, and drugs. The Boc (tert-butoxycarbonyl) group acts as a protective group for amines, enabling selective reactions in multi-step syntheses.
In drug development, it is utilized to create prodrugs or improve the pharmacokinetic properties of therapeutic agents by enhancing water solubility and reducing immunogenicity. Additionally, it is employed in the design of linker molecules for antibody-drug conjugates (ADCs), where it connects the antibody to the cytotoxic drug, ensuring controlled release and stability.
In material science, N-Boc-PEG5-alcohol is used to functionalize surfaces or polymers, enhancing biocompatibility for applications in medical devices or drug delivery systems. Its versatility makes it a crucial reagent in both pharmaceutical research and industrial applications.
Product Specification:
Test | Specification |
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PURITY | 96.5-100 |
Infrared spectrum | Conforms to Structure |
APPEARANCE | Colorless to light yellow Liquid |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.100 | 10-20 days | $82.58 |
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0.250 | 10-20 days | $114.83 |
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1.000 | 10-20 days | $302.02 |
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5.000 | 10-20 days | $1,027.20 |
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N-Boc-PEG5-alcohol
N-Boc-PEG5-alcohol is widely used in organic synthesis and bioconjugation due to its unique properties. Its PEG (polyethylene glycol) spacer provides solubility and flexibility, making it valuable for modifying biomolecules like peptides, proteins, and drugs. The Boc (tert-butoxycarbonyl) group acts as a protective group for amines, enabling selective reactions in multi-step syntheses.
In drug development, it is utilized to create prodrugs or improve the pharmacokinetic properties of therapeutic agents by enhancing water solubility and reducing immunogenicity. Additionally, it is employed in the design of linker molecules for antibody-drug conjugates (ADCs), where it connects the antibody to the cytotoxic drug, ensuring controlled release and stability.
In material science, N-Boc-PEG5-alcohol is used to functionalize surfaces or polymers, enhancing biocompatibility for applications in medical devices or drug delivery systems. Its versatility makes it a crucial reagent in both pharmaceutical research and industrial applications.
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