N-Boc-PEG5-alcohol

97%

  • Product Code: 76703
  CAS:    1404111-67-6
Molecular Weight: 337.41 g./mol Molecular Formula: C₁₅H₃₁NO₇
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition:  -20°C
Product Description: N-Boc-PEG5-alcohol is widely used in organic synthesis and bioconjugation due to its unique properties. Its PEG (polyethylene glycol) spacer provides solubility and flexibility, making it valuable for modifying biomolecules like peptides, proteins, and drugs. The Boc (tert-butoxycarbonyl) group acts as a protective group for amines, enabling selective reactions in multi-step syntheses. In drug development, it is utilized to create prodrugs or improve the pharmacokinetic properties of therapeutic agents by enhancing water solubility and reducing immunogenicity. Additionally, it is employed in the design of linker molecules for antibody-drug conjugates (ADCs), where it connects the antibody to the cytotoxic drug, ensuring controlled release and stability. In material science, N-Boc-PEG5-alcohol is used to functionalize surfaces or polymers, enhancing biocompatibility for applications in medical devices or drug delivery systems. Its versatility makes it a crucial reagent in both pharmaceutical research and industrial applications.
Product Specification:
Test Specification
PURITY 96.5-100
Infrared spectrum Conforms to Structure
APPEARANCE Colorless to light yellow Liquid
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.100 10-20 days $82.58
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0.250 10-20 days $114.83
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1.000 10-20 days $302.02
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5.000 10-20 days $1,027.20
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N-Boc-PEG5-alcohol
N-Boc-PEG5-alcohol is widely used in organic synthesis and bioconjugation due to its unique properties. Its PEG (polyethylene glycol) spacer provides solubility and flexibility, making it valuable for modifying biomolecules like peptides, proteins, and drugs. The Boc (tert-butoxycarbonyl) group acts as a protective group for amines, enabling selective reactions in multi-step syntheses. In drug development, it is utilized to create prodrugs or improve the pharmacokinetic properties of therapeutic agents by enhancing water solubility and reducing immunogenicity. Additionally, it is employed in the design of linker molecules for antibody-drug conjugates (ADCs), where it connects the antibody to the cytotoxic drug, ensuring controlled release and stability. In material science, N-Boc-PEG5-alcohol is used to functionalize surfaces or polymers, enhancing biocompatibility for applications in medical devices or drug delivery systems. Its versatility makes it a crucial reagent in both pharmaceutical research and industrial applications.
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