17-DMAG (Alvespimycin) HCl
≥98%
- Product Code: 76967
CAS:
467214-21-7
| Molecular Weight: | 653.21 g./mol | Molecular Formula: | C₃₂H₄₈N₄O₈HCl |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used primarily in cancer research, it acts as an inhibitor of heat shock protein 90 (HSP90), a protein that supports tumor growth. It is studied for its potential to disrupt cancer cell survival by degrading client proteins essential for tumor progression. Additionally, it is explored in combination therapies to enhance the effectiveness of other anticancer drugs. Its role in neurodegenerative diseases is also under investigation, as HSP90 inhibition may help in managing conditions like Alzheimer’s and Parkinson’s by reducing protein misfolding and aggregation.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Very Dark Purple Solid |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | €51.71 |
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| 0.025 | 10-20 days | €168.05 |
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| 0.100 | 10-20 days | €641.08 |
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17-DMAG (Alvespimycin) HCl
Used primarily in cancer research, it acts as an inhibitor of heat shock protein 90 (HSP90), a protein that supports tumor growth. It is studied for its potential to disrupt cancer cell survival by degrading client proteins essential for tumor progression. Additionally, it is explored in combination therapies to enhance the effectiveness of other anticancer drugs. Its role in neurodegenerative diseases is also under investigation, as HSP90 inhibition may help in managing conditions like Alzheimer’s and Parkinson’s by reducing protein misfolding and aggregation.
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| INCI | - |
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