RI-1
≥98%
- Product Code: 77757
CAS:
415713-60-9
| Molecular Weight: | 361.61 g./mol | Molecular Formula: | C₁₄H₁₁Cl₃N₂O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
RI-1 is primarily used in scientific research, particularly in the field of DNA repair studies. It is known to inhibit the activity of the Mre11-Rad50-Nbs1 (MRN) complex, which plays a critical role in the cellular response to DNA double-strand breaks. By inhibiting this complex, RI-1 helps researchers understand the mechanisms of DNA repair pathways, including homologous recombination. This makes it a valuable tool in studying cancer biology, as defects in DNA repair mechanisms are often associated with tumor development and resistance to treatments like chemotherapy and radiation. Additionally, RI-1 is used to explore potential therapeutic strategies targeting DNA repair processes in various diseases.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | yellow to orange powder |
| PURITY | 97.5-100 |
| SOLUBILITY | DMSO: 10 mg/mL, clear |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $298.84 |
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| 0.250 | 10-20 days | $600.20 |
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RI-1
RI-1 is primarily used in scientific research, particularly in the field of DNA repair studies. It is known to inhibit the activity of the Mre11-Rad50-Nbs1 (MRN) complex, which plays a critical role in the cellular response to DNA double-strand breaks. By inhibiting this complex, RI-1 helps researchers understand the mechanisms of DNA repair pathways, including homologous recombination. This makes it a valuable tool in studying cancer biology, as defects in DNA repair mechanisms are often associated with tumor development and resistance to treatments like chemotherapy and radiation. Additionally, RI-1 is used to explore potential therapeutic strategies targeting DNA repair processes in various diseases.
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