4-(Benzyloxy)-2-fluorophenylboronic acid
96%
- Product Code: 90729
Alias:
4-Benzyloxy-2-fluorophenylboronic acid
CAS:
166744-78-1
| Molecular Weight: | 246.04 g./mol | Molecular Formula: | C₁₃H₁₂BFO₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD02093064 | |
| Melting Point: | 151 °C | Boiling Point: | |
| Density: | Storage Condition: | 2~8°C |
Product Description:
4-(Benzyloxy)-2-fluorophenylboronic acid is primarily utilized in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is widely employed to form carbon-carbon bonds, making it valuable in the production of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group acts as a key functional moiety, enabling the coupling with aryl or vinyl halides in the presence of a palladium catalyst. Additionally, it can be used in the development of bioactive compounds, where the fluorine atom enhances metabolic stability and binding affinity. Its benzyloxy group also provides a protective function during multi-step synthetic processes, allowing for selective deprotection when needed.
Product Specification:
| Test | Specification |
|---|---|
| PURITYHPLC | 96-100 |
| MELTING POINT C | 151-155 |
| INFRARED SPECTRUM | Conforms to structure |
| PROTON NMR SPECTURM | Conforms to structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | $50.63 |
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| 1.000 | 10-20 days | $115.72 |
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| 5.000 | 10-20 days | $461.07 |
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4-(Benzyloxy)-2-fluorophenylboronic acid
4-(Benzyloxy)-2-fluorophenylboronic acid is primarily utilized in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction is widely employed to form carbon-carbon bonds, making it valuable in the production of pharmaceuticals, agrochemicals, and advanced materials. Its boronic acid group acts as a key functional moiety, enabling the coupling with aryl or vinyl halides in the presence of a palladium catalyst. Additionally, it can be used in the development of bioactive compounds, where the fluorine atom enhances metabolic stability and binding affinity. Its benzyloxy group also provides a protective function during multi-step synthetic processes, allowing for selective deprotection when needed.
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