H-Arg(Pbf)-OH

97%

  • Product Code: 97579
  CAS:    200115-86-2
Molecular Weight: 426.53 g./mol Molecular Formula: C₁₉H₃₀N₄O₅S
EC Number: MDL Number: MFCD00236797
Melting Point: Boiling Point: 636.9°C
Density: Storage Condition: room temperature, dry
Product Description: This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of arginine, where the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain during the synthesis process. This protection is crucial to prevent unwanted side reactions and ensure the correct sequence of amino acids in the peptide chain. After the peptide synthesis is complete, the Pbf group can be removed using standard deprotection methods, such as treatment with trifluoroacetic acid (TFA). This compound is essential for producing high-purity peptides, which are used in various research applications, including drug development, biochemical studies, and the production of therapeutic peptides. Its stability and compatibility with SPPS make it a valuable reagent in the field of peptide chemistry.
Product Specification:
Test Specification
APPEARANCE White to off-white solid
PURITY 96.5-100
Infrared spectrum Conforms to Structure
NMR Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.250 10-20 days $12.46
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-
1.000 10-20 days $21.60
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-
5.000 10-20 days $74.34
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H-Arg(Pbf)-OH
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of arginine, where the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain during the synthesis process. This protection is crucial to prevent unwanted side reactions and ensure the correct sequence of amino acids in the peptide chain. After the peptide synthesis is complete, the Pbf group can be removed using standard deprotection methods, such as treatment with trifluoroacetic acid (TFA). This compound is essential for producing high-purity peptides, which are used in various research applications, including drug development, biochemical studies, and the production of therapeutic peptides. Its stability and compatibility with SPPS make it a valuable reagent in the field of peptide chemistry.
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