H-Arg(Pbf)-OH
97%
- Product Code: 97579
CAS:
200115-86-2
Molecular Weight: | 426.53 g./mol | Molecular Formula: | C₁₉H₃₀N₄O₅S |
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EC Number: | MDL Number: | MFCD00236797 | |
Melting Point: | Boiling Point: | 636.9°C | |
Density: | Storage Condition: | room temperature, dry |
Product Description:
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of arginine, where the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain during the synthesis process. This protection is crucial to prevent unwanted side reactions and ensure the correct sequence of amino acids in the peptide chain. After the peptide synthesis is complete, the Pbf group can be removed using standard deprotection methods, such as treatment with trifluoroacetic acid (TFA). This compound is essential for producing high-purity peptides, which are used in various research applications, including drug development, biochemical studies, and the production of therapeutic peptides. Its stability and compatibility with SPPS make it a valuable reagent in the field of peptide chemistry.
Product Specification:
Test | Specification |
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APPEARANCE | White to off-white solid |
PURITY | 96.5-100 |
Infrared spectrum | Conforms to Structure |
NMR | Conforms to Structure |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.250 | 10-20 days | $12.46 |
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1.000 | 10-20 days | $21.60 |
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5.000 | 10-20 days | $74.34 |
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H-Arg(Pbf)-OH
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of arginine, where the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain during the synthesis process. This protection is crucial to prevent unwanted side reactions and ensure the correct sequence of amino acids in the peptide chain. After the peptide synthesis is complete, the Pbf group can be removed using standard deprotection methods, such as treatment with trifluoroacetic acid (TFA). This compound is essential for producing high-purity peptides, which are used in various research applications, including drug development, biochemical studies, and the production of therapeutic peptides. Its stability and compatibility with SPPS make it a valuable reagent in the field of peptide chemistry.
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