JC-1
>95%
- Product Code: 98423
CAS:
3520-43-2
| Molecular Weight: | 652.23 g./mol | Molecular Formula: | C₂₅H₂₇Cl₄IN₄ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
JC-1 is widely used in biomedical research as a fluorescent dye to assess mitochondrial health and function. It is particularly valuable in studying mitochondrial membrane potential, a key indicator of cellular energy status and apoptosis. When applied to cells, JC-1 accumulates in mitochondria and exhibits a color shift from green to red fluorescence as the membrane potential increases. This property allows researchers to distinguish between healthy, high-potential mitochondria and depolarized, low-potential mitochondria. It is commonly employed in studies related to cancer, neurodegenerative diseases, and drug toxicity, where mitochondrial dysfunction plays a critical role. Additionally, JC-1 is utilized in flow cytometry and fluorescence microscopy to monitor changes in mitochondrial activity in response to various cellular stimuli or treatments.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Purple to Red to Purple-red to Reddish-brown Solid |
| PURITY | 95.0-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | $573.18 |
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| 0.050 | 10-20 days | $2,242.09 |
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JC-1
JC-1 is widely used in biomedical research as a fluorescent dye to assess mitochondrial health and function. It is particularly valuable in studying mitochondrial membrane potential, a key indicator of cellular energy status and apoptosis. When applied to cells, JC-1 accumulates in mitochondria and exhibits a color shift from green to red fluorescence as the membrane potential increases. This property allows researchers to distinguish between healthy, high-potential mitochondria and depolarized, low-potential mitochondria. It is commonly employed in studies related to cancer, neurodegenerative diseases, and drug toxicity, where mitochondrial dysfunction plays a critical role. Additionally, JC-1 is utilized in flow cytometry and fluorescence microscopy to monitor changes in mitochondrial activity in response to various cellular stimuli or treatments.
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