(S,R,S)-AHPC-PEG3-NH2 hydrochloride
≥99%
- Product Code: 99247
CAS:
2097971-11-2
| Molecular Weight: | 656.23 g./mol | Molecular Formula: | C₃₀H₄₆ClN₅O₇S |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of Proteolysis-Targeting Chimeras (PROTACs). It serves as a key linker molecule, connecting the target protein binder to the E3 ubiquitin ligase recruiter. The inclusion of the PEG3 spacer enhances the flexibility and solubility of the molecule, which is crucial for efficient protein degradation. Its application is significant in drug discovery and therapeutic research, especially in targeting disease-causing proteins that are traditionally considered "undruggable." The hydrochloride form ensures stability and improves handling in various experimental setups.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Light yellow to brown Solid |
| PURITY | 99-100 |
| 1 H NMR Spectrum | Consistent with structure |
| Infrared spectrum | Conforms to Structure |
| LCMS | Consistent with structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | $240.02 |
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| 0.025 | 10-20 days | $480.05 |
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(S,R,S)-AHPC-PEG3-NH2 hydrochloride
This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of Proteolysis-Targeting Chimeras (PROTACs). It serves as a key linker molecule, connecting the target protein binder to the E3 ubiquitin ligase recruiter. The inclusion of the PEG3 spacer enhances the flexibility and solubility of the molecule, which is crucial for efficient protein degradation. Its application is significant in drug discovery and therapeutic research, especially in targeting disease-causing proteins that are traditionally considered "undruggable." The hydrochloride form ensures stability and improves handling in various experimental setups.
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