(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride
99%
- Product Code: 113879
Alias:
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride; Methoxy-trifluoromethylphenylacetyl chloride
CAS:
39637-99-5
| Molecular Weight: | 252.62 g./mol | Molecular Formula: | C₁₀H₈ClF₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00044400 | |
| Melting Point: | Boiling Point: | 99 °C /1.6kPa | |
| Density: | 1.35 g/mL at 25 °C(lit.) | Storage Condition: | -20°C, dry, inert gas |
Product Description:
This chemical is widely used as a chiral derivatizing agent in organic synthesis and analytical chemistry. It is particularly valuable for the resolution and determination of enantiomeric purity of chiral compounds, such as alcohols, amines, and amino acids. By forming diastereomeric derivatives, it enables the separation and quantification of enantiomers using techniques like HPLC or NMR. Additionally, it serves as a key reagent in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals, where precise stereochemistry is critical for biological activity. Its trifluoromethyl group enhances reactivity and selectivity, making it a preferred choice in asymmetric synthesis and chiral analysis.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Colorless To Light Yellow To Yellow Liquid |
| Purity (%) | 98.5-100 |
| Specific Rotation [a]20/D(c=6.4 In Carbon Tetrachloride) | -139.0--135.0 |
| Tetrachloride | -139.0 -135.0° |
| Refractive Index (20 Degree Celsius, 589 Nm) | 1.4675-1.4715 |
| Infrared Spectrum | Conforms To Structure |
| NMR | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿3,780.00 |
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(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride
This chemical is widely used as a chiral derivatizing agent in organic synthesis and analytical chemistry. It is particularly valuable for the resolution and determination of enantiomeric purity of chiral compounds, such as alcohols, amines, and amino acids. By forming diastereomeric derivatives, it enables the separation and quantification of enantiomers using techniques like HPLC or NMR. Additionally, it serves as a key reagent in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals, where precise stereochemistry is critical for biological activity. Its trifluoromethyl group enhances reactivity and selectivity, making it a preferred choice in asymmetric synthesis and chiral analysis.
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