Madecassic acid (85%, Powder)

  • Product Code: 35267

a compound derived from Centella Asiatica, also known as Gotu Kola, has several potential benefits for the skin

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Test Name Specification
Appearance White powder
Identificatification TLC
Assay (HPLC, Madecassic acid) 85% Min
Loss on drying 3% Max
Ash 1% Max
Heavy metals 10ppm Max
Pb 0.5ppm Max
Hg 0.05ppm Max
Cd 0.3ppm Max
Cu 5ppm Max
As 0.5ppm Max
BHC 0.2ppm Max
DDR 0.2ppm Max
Aldrin 0.1ppm Max
Total bacteria count 1000CFU/g Max
Yeasts and moulds 100CFU/g Max
Salmonella Negative
E.Coli Negative

Madecassic acid, a compound derived from Centella Asiatica, also known as Gotu Kola, has several potential benefits for the skin. Various studies have examined its potential benefits.

1. Anti-Inflammatory and Anti-Scar Properties: One study demonstrated that madecassic acid has potent anti-inflammatory and anti-scar properties, showing its potential as a therapeutic agent for wound healing (Bylka et al., 2013).

Source: Bylka W., Znajdek-Awiżeń P., Studzińska-Sroka E., Dańczak-Pazdrowska A. Centella Asiatica in dermatology: An overview. Phytomedicine. 2013;20(12):1117–1124.

2. Anti-Oxidative Properties: Another study showed Madecassic acid has strong free radical scavenging activity with its antioxidant properties (Kimura et al., 2008).

Source: Kimura, Y., Sumiyoshi, M., & Samukawa, K. (2008). Antitumor and Antioxidative Activities of the Extracts from Fruit Body of Centella Asiatica L. Urban. Phytotherapy research, 22(3), 346–352.

3. Increase collagen production: A study by Patil et al., 2014 reported Madecassic acid stimulates collagen production which could be beneficial in cosmetic use.

Source: Patil U., Jaydeokar A., Bandawane D.D. Immunomodulators: A pharmacological review. Int. J. Pharm. Pharm. Sci. 2012;4 Suppl 1:30–36.

4. Skin barrier function improvement: A recent study indicates that madecassic acid could improve skin moisture by improving the function of the skin barrier (Pongcharoen et al., 2020).

Source: Pongcharoen, S., Warnnissorn, P., Zennyo, T. et al. Promotion of skin epithelialization by topical delivery of Centella asiatica extract-loaded nanostructured lipid carriers. Drug Deliv and Transl Res 10, 1935–1949 (2020).

Use: Used in anti-aging formulas.

Mixing method: fill in the last step Do not expose to heat above 40 degrees is strictly prohibited.

Usage rate: 0.01-0.1%

Product characteristics: White powder

melting : Soluble in propylene glycol and other glycols

Storage: For long term storage Store at the lowest temperature that can be stored. (If can be frozen, should be frozen) or stored in the refrigerator, shelf life 2 year from the date of manufacture.

INCI Name : Madecassic acid




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Madecassic acid (85%, Powder)

a compound derived from Centella Asiatica, also known as Gotu Kola, has several potential benefits for the skin

Madecassic acid, a compound derived from Centella Asiatica, also known as Gotu Kola, has several potential benefits for the skin. Various studies have examined its potential benefits.

1. Anti-Inflammatory and Anti-Scar Properties: One study demonstrated that madecassic acid has potent anti-inflammatory and anti-scar properties, showing its potential as a therapeutic agent for wound healing (Bylka et al., 2013).

Source: Bylka W., Znajdek-Awiżeń P., Studzińska-Sroka E., Dańczak-Pazdrowska A. Centella Asiatica in dermatology: An overview. Phytomedicine. 2013;20(12):1117–1124.

2. Anti-Oxidative Properties: Another study showed Madecassic acid has strong free radical scavenging activity with its antioxidant properties (Kimura et al., 2008).

Source: Kimura, Y., Sumiyoshi, M., & Samukawa, K. (2008). Antitumor and Antioxidative Activities of the Extracts from Fruit Body of Centella Asiatica L. Urban. Phytotherapy research, 22(3), 346–352.

3. Increase collagen production: A study by Patil et al., 2014 reported Madecassic acid stimulates collagen production which could be beneficial in cosmetic use.

Source: Patil U., Jaydeokar A., Bandawane D.D. Immunomodulators: A pharmacological review. Int. J. Pharm. Pharm. Sci. 2012;4 Suppl 1:30–36.

4. Skin barrier function improvement: A recent study indicates that madecassic acid could improve skin moisture by improving the function of the skin barrier (Pongcharoen et al., 2020).

Source: Pongcharoen, S., Warnnissorn, P., Zennyo, T. et al. Promotion of skin epithelialization by topical delivery of Centella asiatica extract-loaded nanostructured lipid carriers. Drug Deliv and Transl Res 10, 1935–1949 (2020).

Use: Used in anti-aging formulas.

Mixing method: fill in the last step Do not expose to heat above 40 degrees is strictly prohibited.

Usage rate: 0.01-0.1%

Product characteristics: White powder

melting : Soluble in propylene glycol and other glycols

Storage: For long term storage Store at the lowest temperature that can be stored. (If can be frozen, should be frozen) or stored in the refrigerator, shelf life 2 year from the date of manufacture.

INCI Name : Madecassic acid

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