WEHI-539
98%
- Product Code: 103274
CAS:
1431866-33-9
| Molecular Weight: | 583.72 g./mol | Molecular Formula: | C₃₁H₂₉N₅O₃S₂ |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
WEHI-539 is primarily utilized in biochemical and pharmacological research due to its role as a selective inhibitor of BCL-XL, a protein involved in regulating apoptosis (programmed cell death). Its application is significant in studying cancer biology, as BCL-XL is often overexpressed in various cancers, contributing to tumor survival and resistance to chemotherapy. By inhibiting BCL-XL, researchers can explore mechanisms to induce apoptosis in cancer cells, potentially leading to the development of targeted cancer therapies. Additionally, it is used to investigate the role of BCL-XL in other diseases where apoptosis regulation is disrupted, such as neurodegenerative disorders. Its use in laboratory settings helps in understanding cellular pathways and evaluating the efficacy of potential therapeutic agents.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.002 | 10-20 days | ฿24,680.00 |
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| 0.005 | 10-20 days | ฿51,190.00 |
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WEHI-539
WEHI-539 is primarily utilized in biochemical and pharmacological research due to its role as a selective inhibitor of BCL-XL, a protein involved in regulating apoptosis (programmed cell death). Its application is significant in studying cancer biology, as BCL-XL is often overexpressed in various cancers, contributing to tumor survival and resistance to chemotherapy. By inhibiting BCL-XL, researchers can explore mechanisms to induce apoptosis in cancer cells, potentially leading to the development of targeted cancer therapies. Additionally, it is used to investigate the role of BCL-XL in other diseases where apoptosis regulation is disrupted, such as neurodegenerative disorders. Its use in laboratory settings helps in understanding cellular pathways and evaluating the efficacy of potential therapeutic agents.
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