Simvastatin Acyl-β-D-glucuronide
≥98%
- Product Code: 103550
CAS:
463962-56-3
| Molecular Weight: | 612.71 g./mol | Molecular Formula: | C₃₁H₄₈O₁₂ |
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| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Simvastatin Acyl-β-D-glucuronide is primarily used in research and pharmaceutical studies as a metabolite of simvastatin, a widely prescribed cholesterol-lowering drug. Its applications include:
- **Metabolic Studies**: It is utilized to understand the metabolic pathways and biotransformation processes of simvastatin in the human body. This helps in evaluating the drug's efficacy and safety profile.
- **Drug Interaction Research**: It serves as a key compound in studying potential drug interactions, particularly how simvastatin interacts with other medications or enzymes in the liver.
- **Analytical Reference Standard**: It is employed as a reference standard in analytical methods, such as liquid chromatography-mass spectrometry (LC-MS), to quantify and identify simvastatin and its metabolites in biological samples.
- **Toxicity Assessment**: Researchers use it to assess the potential toxicological effects of simvastatin metabolites, contributing to the development of safer therapeutic strategies.
- **Pharmacokinetic Studies**: It aids in understanding the absorption, distribution, metabolism, and excretion (ADME) properties of simvastatin, which are critical for optimizing dosage and treatment regimens.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | ฿103,500.00 |
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Simvastatin Acyl-β-D-glucuronide
Simvastatin Acyl-β-D-glucuronide is primarily used in research and pharmaceutical studies as a metabolite of simvastatin, a widely prescribed cholesterol-lowering drug. Its applications include:
- **Metabolic Studies**: It is utilized to understand the metabolic pathways and biotransformation processes of simvastatin in the human body. This helps in evaluating the drug's efficacy and safety profile.
- **Drug Interaction Research**: It serves as a key compound in studying potential drug interactions, particularly how simvastatin interacts with other medications or enzymes in the liver.
- **Analytical Reference Standard**: It is employed as a reference standard in analytical methods, such as liquid chromatography-mass spectrometry (LC-MS), to quantify and identify simvastatin and its metabolites in biological samples.
- **Toxicity Assessment**: Researchers use it to assess the potential toxicological effects of simvastatin metabolites, contributing to the development of safer therapeutic strategies.
- **Pharmacokinetic Studies**: It aids in understanding the absorption, distribution, metabolism, and excretion (ADME) properties of simvastatin, which are critical for optimizing dosage and treatment regimens.
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