Alrestatin
99%
- Product Code: 103570
CAS:
51411-04-2
Molecular Weight: | 255.23 g./mol | Molecular Formula: | C₁₄H₉NO₄ |
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EC Number: | MDL Number: | MFCD00181399 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | -20℃ |
Product Description:
Alrestatin is primarily known for its application in the field of medical research, particularly in the study of diabetes and its complications. It acts as an inhibitor of aldose reductase, an enzyme that plays a significant role in the polyol pathway. By inhibiting this enzyme, Alrestatin helps in reducing the accumulation of sorbitol in cells, which is a key factor in the development of diabetic complications such as neuropathy, retinopathy, and nephropathy.
In experimental settings, Alrestatin has been used to investigate the potential therapeutic benefits of aldose reductase inhibition. Studies have shown that it can help in preventing or delaying the onset of diabetic complications by mitigating the harmful effects of high glucose levels on various tissues. This makes it a valuable tool in understanding the biochemical pathways involved in diabetes and in the development of new treatments aimed at improving the quality of life for diabetic patients.
Additionally, Alrestatin has been utilized in biochemical assays to study the kinetics and mechanism of aldose reductase inhibition. This research contributes to the broader understanding of enzyme inhibition and aids in the design of more effective and selective inhibitors for clinical use. Overall, Alrestatin's role in diabetes research underscores its importance in advancing medical science and developing innovative therapeutic strategies.
Product Specification:
Test | Specification |
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Appearance | White To Off-White Powder |
Purity (%) | 98.5-100 |
Infrared Spectrum | Conforms To Structure |
NMR | Conforms To Structure |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.005 | 10-20 days | ฿7,980.00 |
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0.025 | 10-20 days | ฿21,880.00 |
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0.100 | 10-20 days | ฿66,000.00 |
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Alrestatin
Alrestatin is primarily known for its application in the field of medical research, particularly in the study of diabetes and its complications. It acts as an inhibitor of aldose reductase, an enzyme that plays a significant role in the polyol pathway. By inhibiting this enzyme, Alrestatin helps in reducing the accumulation of sorbitol in cells, which is a key factor in the development of diabetic complications such as neuropathy, retinopathy, and nephropathy.
In experimental settings, Alrestatin has been used to investigate the potential therapeutic benefits of aldose reductase inhibition. Studies have shown that it can help in preventing or delaying the onset of diabetic complications by mitigating the harmful effects of high glucose levels on various tissues. This makes it a valuable tool in understanding the biochemical pathways involved in diabetes and in the development of new treatments aimed at improving the quality of life for diabetic patients.
Additionally, Alrestatin has been utilized in biochemical assays to study the kinetics and mechanism of aldose reductase inhibition. This research contributes to the broader understanding of enzyme inhibition and aids in the design of more effective and selective inhibitors for clinical use. Overall, Alrestatin's role in diabetes research underscores its importance in advancing medical science and developing innovative therapeutic strategies.
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