Fmoc-Ser(HPO3Bzl)-OH
≥97.0% (HPLC)
- Product Code: 104096
Alias:
Fmoc-benzyl serine phosphate; N-fluorenylmethoxycarbonyl-O-(benzylphosphoryl)-L-serine
CAS:
158171-14-3
| Molecular Weight: | 497.43 g./mol | Molecular Formula: | C₂₅H₂₄NO₈P |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00797869 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2~8°C |
Product Description:
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino group, while the HPO3Bzl (benzyl phosphate) group protects the serine side chain. This protection strategy allows for the selective deprotection and coupling of amino acids during the synthesis process. It is especially useful in constructing phosphorylated peptides, which are important in studying protein phosphorylation, a key regulatory mechanism in cellular signaling pathways. The compound ensures precise control over the incorporation of serine residues with phosphate groups, enabling the production of biologically relevant peptides for research and therapeutic applications.
Product Specification:
| Test | Specification |
|---|---|
| Purity (HPLC) | 97-100 |
| Infrared Spectrometry | Conforms To Structure |
| Proton NMR Spectrum | Conforms To Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿1,040.00 |
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-
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| 1.000 | 10-20 days | ฿3,030.00 |
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| 5.000 | 10-20 days | ฿12,440.00 |
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-
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Fmoc-Ser(HPO3Bzl)-OH
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino group, while the HPO3Bzl (benzyl phosphate) group protects the serine side chain. This protection strategy allows for the selective deprotection and coupling of amino acids during the synthesis process. It is especially useful in constructing phosphorylated peptides, which are important in studying protein phosphorylation, a key regulatory mechanism in cellular signaling pathways. The compound ensures precise control over the incorporation of serine residues with phosphate groups, enabling the production of biologically relevant peptides for research and therapeutic applications.
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| Stable in pH range | - |
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