Fmoc-D-Pen(pMeOBzl)-OH
98%
- Product Code: 105039
CAS:
159618-54-9
Molecular Weight: | 491.60 g./mol | Molecular Formula: | C₂₈H₂₉NO₅S |
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EC Number: | MDL Number: | MFCD02094102 | |
Melting Point: | Boiling Point: | 692.2±55.0 °C(Predicted) | |
Density: | 1.257±0.06 g/cm3(Predicted) | Storage Condition: | Room temperature, sealed, dry |
Product Description:
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (9-fluorenylmethoxycarbonyl) group acts as a temporary protecting group for the amine functionality during the synthesis process. The pMeOBzl (para-methoxybenzyl) group protects the thiol side chain of the penicillamine residue, preventing unwanted side reactions. This compound is especially valuable in the synthesis of peptides containing penicillamine, which are often studied for their potential therapeutic applications, including chelation therapy and the treatment of heavy metal poisoning. Additionally, peptides synthesized using this derivative may be explored for their role in modulating immune responses or as components in drug delivery systems. The orthogonal protection strategy (Fmoc for the amine and pMeOBzl for the thiol) allows for selective deprotection and efficient peptide chain elongation.
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.100 | 10-20 days | ฿21,492.00 |
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Fmoc-D-Pen(pMeOBzl)-OH
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (9-fluorenylmethoxycarbonyl) group acts as a temporary protecting group for the amine functionality during the synthesis process. The pMeOBzl (para-methoxybenzyl) group protects the thiol side chain of the penicillamine residue, preventing unwanted side reactions. This compound is especially valuable in the synthesis of peptides containing penicillamine, which are often studied for their potential therapeutic applications, including chelation therapy and the treatment of heavy metal poisoning. Additionally, peptides synthesized using this derivative may be explored for their role in modulating immune responses or as components in drug delivery systems. The orthogonal protection strategy (Fmoc for the amine and pMeOBzl for the thiol) allows for selective deprotection and efficient peptide chain elongation.
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