Fmoc-Trp(Boc)-OH

97.0%

  • Product Code: 105105
  Alias:    Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-Butoxycarbonyl-L-Tryptophan, Fmoc-L-Tryptophan(Boc)-OH
  CAS:    143824-78-6
Molecular Weight: 526.58 g./mol Molecular Formula: C₃₁H₃₀N₂O₆
EC Number: MDL Number: MFCD00153366
Melting Point: Boiling Point:
Density: Storage Condition: 2~8°C
Product Description: This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid building block, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality, and the Boc (tert-butyloxycarbonyl) group protects the indole side chain of tryptophan. Its primary application is in the production of peptides for research and pharmaceutical purposes, ensuring precise and controlled assembly of peptide chains. It is especially valuable in synthesizing peptides containing tryptophan residues, which are prone to oxidation or side reactions during synthesis. The compound is also utilized in the development of peptide-based drugs, diagnostics, and biochemical tools, contributing to advancements in medicinal chemistry and biotechnology.
Product Specification:
Test Specification
Appearance White To Orange To Green Powder To Crystal
Purity (HPLC) 97-100
Melting Point 90-100
Infrared Spectrum Conforms To Structure
Specific Rotation [a]20/D(C=1, DMF) -18.0- -22.0°
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
1.000 10-20 days $19.59
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-
5.000 10-20 days $64.29
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25.000 10-20 days $225.01
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-
100.000 10-20 days $817.68
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Fmoc-Trp(Boc)-OH
This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid building block, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality, and the Boc (tert-butyloxycarbonyl) group protects the indole side chain of tryptophan. Its primary application is in the production of peptides for research and pharmaceutical purposes, ensuring precise and controlled assembly of peptide chains. It is especially valuable in synthesizing peptides containing tryptophan residues, which are prone to oxidation or side reactions during synthesis. The compound is also utilized in the development of peptide-based drugs, diagnostics, and biochemical tools, contributing to advancements in medicinal chemistry and biotechnology.
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