Fmoc-Trp(Boc)-OH
97.0%
- Product Code: 105105
Alias:
Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-Butoxycarbonyl-L-Tryptophan, Fmoc-L-Tryptophan(Boc)-OH
CAS:
143824-78-6
| Molecular Weight: | 526.58 g./mol | Molecular Formula: | C₃₁H₃₀N₂O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00153366 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2~8°C |
Product Description:
This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid building block, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality, and the Boc (tert-butyloxycarbonyl) group protects the indole side chain of tryptophan. Its primary application is in the production of peptides for research and pharmaceutical purposes, ensuring precise and controlled assembly of peptide chains. It is especially valuable in synthesizing peptides containing tryptophan residues, which are prone to oxidation or side reactions during synthesis. The compound is also utilized in the development of peptide-based drugs, diagnostics, and biochemical tools, contributing to advancements in medicinal chemistry and biotechnology.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White To Orange To Green Powder To Crystal |
| Purity (HPLC) | 97-100 |
| Melting Point | 90-100 |
| Infrared Spectrum | Conforms To Structure |
| Specific Rotation [a]20/D(C=1, DMF) | -18.0- -22.0° |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | ฿390.00 |
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| 5.000 | 10-20 days | ฿1,280.00 |
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| 25.000 | 10-20 days | ฿4,480.00 |
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| 100.000 | 10-20 days | ฿16,280.00 |
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Fmoc-Trp(Boc)-OH
This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid building block, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality, and the Boc (tert-butyloxycarbonyl) group protects the indole side chain of tryptophan. Its primary application is in the production of peptides for research and pharmaceutical purposes, ensuring precise and controlled assembly of peptide chains. It is especially valuable in synthesizing peptides containing tryptophan residues, which are prone to oxidation or side reactions during synthesis. The compound is also utilized in the development of peptide-based drugs, diagnostics, and biochemical tools, contributing to advancements in medicinal chemistry and biotechnology.
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