Thalidomide-amido-PEG2-NH2
≥95%
- Product Code: 106451
CAS:
2380273-72-1
| Molecular Weight: | 418.40 g./mol | Molecular Formula: | C₁₉H₂₂N₄O₇ |
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| Density: | Storage Condition: | 2-8°C, dry, sealed |
Product Description:
Thalidomide-amido-PEG2-NH2 is primarily utilized in the development of PROTACs (Proteolysis Targeting Chimeras), a cutting-edge technology in drug discovery. This compound serves as a key linker component that connects a target protein-binding ligand to an E3 ubiquitin ligase recruiter. By facilitating the ubiquitination and subsequent degradation of specific proteins, it plays a crucial role in targeting disease-causing proteins that are traditionally considered "undruggable." Its application is particularly significant in cancer research, where it aids in the selective degradation of oncogenic proteins, offering a novel therapeutic strategy. Additionally, its use extends to neurodegenerative and inflammatory diseases, providing a versatile tool for advancing targeted protein degradation therapies.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | ฿19,800.00 |
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Thalidomide-amido-PEG2-NH2
Thalidomide-amido-PEG2-NH2 is primarily utilized in the development of PROTACs (Proteolysis Targeting Chimeras), a cutting-edge technology in drug discovery. This compound serves as a key linker component that connects a target protein-binding ligand to an E3 ubiquitin ligase recruiter. By facilitating the ubiquitination and subsequent degradation of specific proteins, it plays a crucial role in targeting disease-causing proteins that are traditionally considered "undruggable." Its application is particularly significant in cancer research, where it aids in the selective degradation of oncogenic proteins, offering a novel therapeutic strategy. Additionally, its use extends to neurodegenerative and inflammatory diseases, providing a versatile tool for advancing targeted protein degradation therapies.
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