Thalidomide-NH-CBP/p300 ligand 2
≥98%
- Product Code: 106463
CAS:
2484739-21-9
| Molecular Weight: | 922.03 g./mol | Molecular Formula: | C₄₈H₅₇F₂N₁₁O₆ |
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| Density: | Storage Condition: | -20°C, dry, sealed |
Product Description:
Thalidomide-NH-CBP/p300 ligand 2 is primarily used in targeted protein degradation research. It functions as a bifunctional molecule, combining a thalidomide derivative with a ligand specific to CBP/p300 proteins. This design allows it to recruit the E3 ubiquitin ligase machinery to CBP/p300, marking these proteins for proteasomal degradation. Its application is significant in studying epigenetic regulation, as CBP/p300 are key transcriptional coactivators involved in gene expression modulation. Researchers utilize this compound to explore the roles of CBP/p300 in diseases like cancer, where these proteins are often dysregulated. Additionally, it serves as a tool for probing the therapeutic potential of selectively degrading CBP/p300 in pathological conditions.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿99,000.00 |
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Thalidomide-NH-CBP/p300 ligand 2
Thalidomide-NH-CBP/p300 ligand 2 is primarily used in targeted protein degradation research. It functions as a bifunctional molecule, combining a thalidomide derivative with a ligand specific to CBP/p300 proteins. This design allows it to recruit the E3 ubiquitin ligase machinery to CBP/p300, marking these proteins for proteasomal degradation. Its application is significant in studying epigenetic regulation, as CBP/p300 are key transcriptional coactivators involved in gene expression modulation. Researchers utilize this compound to explore the roles of CBP/p300 in diseases like cancer, where these proteins are often dysregulated. Additionally, it serves as a tool for probing the therapeutic potential of selectively degrading CBP/p300 in pathological conditions.
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