(S)-3,3-Difluoro-5-(hydroxymethyl)pyrrolidin-2-one

95%

  • Product Code: 113759
  CAS:    255903-84-5
Molecular Weight: 151.11 g./mol Molecular Formula: C₅H₇F₂NO₂
EC Number: MDL Number: MFCD13194160
Melting Point: Boiling Point: 304.1±42.0°C at 760 mmHg
Density: Storage Condition: 2-8°C, dry and sealed
Product Description: This compound is primarily utilized in the pharmaceutical industry as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its unique structure, featuring a difluoro-substituted pyrrolidinone ring, makes it valuable for developing drugs with enhanced metabolic stability and bioavailability. It is often employed in the production of enzyme inhibitors, particularly those targeting proteases and kinases, which are crucial in treating diseases like cancer, viral infections, and inflammatory disorders. Additionally, its chiral center allows for the creation of enantiomerically pure compounds, which is essential for optimizing drug efficacy and minimizing side effects. The hydroxymethyl group further provides a reactive site for chemical modifications, enabling the attachment of various functional groups to tailor the pharmacological properties of the final drug molecule.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.100 10-20 days ฿13,284.00
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0.250 10-20 days ฿26,586.00
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(S)-3,3-Difluoro-5-(hydroxymethyl)pyrrolidin-2-one
This compound is primarily utilized in the pharmaceutical industry as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its unique structure, featuring a difluoro-substituted pyrrolidinone ring, makes it valuable for developing drugs with enhanced metabolic stability and bioavailability. It is often employed in the production of enzyme inhibitors, particularly those targeting proteases and kinases, which are crucial in treating diseases like cancer, viral infections, and inflammatory disorders. Additionally, its chiral center allows for the creation of enantiomerically pure compounds, which is essential for optimizing drug efficacy and minimizing side effects. The hydroxymethyl group further provides a reactive site for chemical modifications, enabling the attachment of various functional groups to tailor the pharmacological properties of the final drug molecule.
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