3-Aminobenzamide
98%
- Product Code: 117831
Alias:
3-aminobenzamide; m-aminobenzamide
CAS:
3544-24-9
Molecular Weight: | 136.15 g./mol | Molecular Formula: | C₇H₈N₂O |
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EC Number: | 222-586-9 | MDL Number: | MFCD00007989 |
Melting Point: | 115-116 °C(lit.) | Boiling Point: | |
Density: | Storage Condition: | room temperature |
Product Description:
3-Aminobenzamide is primarily used as an inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair processes. Its application in research focuses on studying the mechanisms of DNA repair and the role of PARP in cellular responses to DNA damage. It is employed in experimental settings to induce apoptosis in cancer cells by inhibiting PARP, thereby preventing DNA repair and leading to cell death. This makes it a valuable tool in cancer research, particularly in understanding how PARP inhibitors can be used to enhance the effectiveness of chemotherapy and radiation therapy. Additionally, 3-Aminobenzamide is used in studies exploring neurodegenerative diseases, as PARP activation is implicated in neuronal cell death. Its role in modulating inflammation and oxidative stress further extends its utility in biomedical research.
Product Specification:
Test | Specification |
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Purity (HPLC) | 98-100 |
Appearance | White To Grey Powder |
Infrared Spectrum | Conforms To Structure |
Solubility In Methanol | Pass |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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1.000 | 10-20 days | $44.20 |
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5.000 | 10-20 days | $89.90 |
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25.000 | 10-20 days | $393.27 |
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100.000 | 10-20 days | $1,312.41 |
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3-Aminobenzamide
3-Aminobenzamide is primarily used as an inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair processes. Its application in research focuses on studying the mechanisms of DNA repair and the role of PARP in cellular responses to DNA damage. It is employed in experimental settings to induce apoptosis in cancer cells by inhibiting PARP, thereby preventing DNA repair and leading to cell death. This makes it a valuable tool in cancer research, particularly in understanding how PARP inhibitors can be used to enhance the effectiveness of chemotherapy and radiation therapy. Additionally, 3-Aminobenzamide is used in studies exploring neurodegenerative diseases, as PARP activation is implicated in neuronal cell death. Its role in modulating inflammation and oxidative stress further extends its utility in biomedical research.
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