2'-O-tert-Butyldimethylsilyl-N4-acetyl-cytidine
95%
- Product Code: 40421
CAS:
119794-51-3
| Molecular Weight: | 399.51 g./mol | Molecular Formula: | C₁₇H₂₉N₃O₆Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28134645 | |
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| Density: | Storage Condition: | 2-8℃ |
Product Description:
This compound is primarily utilized in the synthesis of modified nucleosides, which are crucial in the development of oligonucleotides for research and therapeutic purposes. It serves as a protected form of cytidine, where the tert-butyldimethylsilyl group safeguards the 2'-hydroxyl position, and the acetyl group protects the N4 position during chemical reactions. This protection is essential in solid-phase oligonucleotide synthesis, enabling the precise construction of RNA sequences. Additionally, it finds application in the study of RNA structure and function, as well as in the development of RNA-based therapeutics, such as siRNA and mRNA vaccines, where modified nucleosides enhance stability and efficacy.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | €1,527.44 |
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2'-O-tert-Butyldimethylsilyl-N4-acetyl-cytidine
This compound is primarily utilized in the synthesis of modified nucleosides, which are crucial in the development of oligonucleotides for research and therapeutic purposes. It serves as a protected form of cytidine, where the tert-butyldimethylsilyl group safeguards the 2'-hydroxyl position, and the acetyl group protects the N4 position during chemical reactions. This protection is essential in solid-phase oligonucleotide synthesis, enabling the precise construction of RNA sequences. Additionally, it finds application in the study of RNA structure and function, as well as in the development of RNA-based therapeutics, such as siRNA and mRNA vaccines, where modified nucleosides enhance stability and efficacy.
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