EAI045
97%
- Product Code: 56100
Alias:
2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide
CAS:
1942114-09-1
| Molecular Weight: | 383.4 g./mol | Molecular Formula: | C₁₉H₁₄FN₃O₃S |
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| EC Number: | MDL Number: | MFCD30187871 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
EAI045 is primarily used in research settings as a targeted inhibitor of mutant forms of the epidermal growth factor receptor (EGFR), particularly those associated with non-small cell lung cancer (NSCLC). It is specifically designed to address resistance mutations, such as T790M, which often develop in patients treated with first-generation EGFR inhibitors. By selectively binding to these mutated receptors, EAI045 helps to block the signaling pathways that promote cancer cell growth and survival. This makes it a valuable tool in studying resistance mechanisms and developing next-generation therapies for EGFR-driven cancers. Its application is largely confined to preclinical studies, where it aids in understanding the molecular basis of drug resistance and evaluating potential therapeutic strategies.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿2,060.00 |
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| 0.250 | 10-20 days | ฿3,090.00 |
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| 1.000 | 10-20 days | ฿11,000.00 |
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EAI045
EAI045 is primarily used in research settings as a targeted inhibitor of mutant forms of the epidermal growth factor receptor (EGFR), particularly those associated with non-small cell lung cancer (NSCLC). It is specifically designed to address resistance mutations, such as T790M, which often develop in patients treated with first-generation EGFR inhibitors. By selectively binding to these mutated receptors, EAI045 helps to block the signaling pathways that promote cancer cell growth and survival. This makes it a valuable tool in studying resistance mechanisms and developing next-generation therapies for EGFR-driven cancers. Its application is largely confined to preclinical studies, where it aids in understanding the molecular basis of drug resistance and evaluating potential therapeutic strategies.
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