Diphenyl phosphoryl azide (DPPA)

97%

  • Product Code: 56694
  Alias:    Diphenylphosphoryl azide (DPPA); diphenylphosphoryl azide
  CAS:    26386-88-9
Molecular Weight: 275.2 g./mol Molecular Formula: C₁₂H₁₀N₃O₃P
EC Number: 247-644-0 MDL Number: MFCD00001987
Melting Point: Boiling Point: 157 °C0.17 mm Hg(lit.)
Density: 1.277 g/mL at 25 °C(lit.) Storage Condition: 2~8°C
Product Description: Diphenyl phosphoryl azide (DPPA) is widely used in organic synthesis, particularly in peptide coupling reactions. It serves as a reagent for converting carboxylic acids into acyl azides, which can then be rearranged to form isocyanates through the Curtius rearrangement. This makes it valuable in the synthesis of amines, ureas, and carbamates. DPPA is also employed in the preparation of heterocycles and in the modification of amino acids or peptides. Its ability to facilitate mild and efficient reactions makes it a preferred choice in pharmaceutical and biochemical research for constructing complex molecular structures. Additionally, it is utilized in polymer chemistry for cross-linking and functionalizing polymers.
Product Specification:
Test Specification
PurityGC 97-100
REFRACTIVE INDEXN20D 1.55-1.554
APPEARANCE COLORLESS TO YELLOW TO AMBER LIQUID
INFRARED SPECTRUM Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
5.000 10-20 days $15.50
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25.000 10-20 days $25.36
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100.000 10-20 days $65.75
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500.000 10-20 days $238.11
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2500.000 10-20 days $1,032.74
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Diphenyl phosphoryl azide (DPPA)
Diphenyl phosphoryl azide (DPPA) is widely used in organic synthesis, particularly in peptide coupling reactions. It serves as a reagent for converting carboxylic acids into acyl azides, which can then be rearranged to form isocyanates through the Curtius rearrangement. This makes it valuable in the synthesis of amines, ureas, and carbamates. DPPA is also employed in the preparation of heterocycles and in the modification of amino acids or peptides. Its ability to facilitate mild and efficient reactions makes it a preferred choice in pharmaceutical and biochemical research for constructing complex molecular structures. Additionally, it is utilized in polymer chemistry for cross-linking and functionalizing polymers.
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