Boc-Cys(Acm)-OH

98%

  • Product Code: 59253
  CAS:    19746-37-3
Molecular Weight: 292.35 g./mol Molecular Formula: C₁₁H₂₀N₂O₅S
EC Number: 243-267-0 MDL Number: MFCD00038252
Melting Point: 111-114 °C Boiling Point:
Density: Storage Condition: 2~8°C, sealed, protected from light
Product Description: This compound is primarily used in peptide synthesis as a protected form of cysteine. The Boc (tert-butoxycarbonyl) group protects the amino group, while the Acm (acetamidomethyl) group protects the thiol side chain of cysteine. This dual protection allows for selective deprotection during the synthesis process, ensuring the integrity of the peptide chain. It is particularly useful in solid-phase peptide synthesis (SPPS) where controlled and sequential addition of amino acids is required. The compound is also employed in the preparation of complex peptides and proteins, especially those involving disulfide bond formation, which is critical for the structural stability and biological activity of many peptides. Its application extends to the development of pharmaceuticals, including peptide-based drugs and therapeutic agents.
Product Specification:
Test Specification
Purity 98-100
300 MHZ NMR SPECTRUM 1H Conforms to Structure
APPEARANCE WHITE TO LIGHT YELLOW POWDER
INFRARED SPECTROMETRY Conforms to Structure
SPECIFIC ROTATIONA20DC1H2O 36.51.5
TLC ANALYSIS ONE SPOT
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
1.000 10-20 days $11.01
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-
5.000 10-20 days $27.13
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-
25.000 10-20 days $91.24
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-
100.000 10-20 days $354.72
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Boc-Cys(Acm)-OH
This compound is primarily used in peptide synthesis as a protected form of cysteine. The Boc (tert-butoxycarbonyl) group protects the amino group, while the Acm (acetamidomethyl) group protects the thiol side chain of cysteine. This dual protection allows for selective deprotection during the synthesis process, ensuring the integrity of the peptide chain. It is particularly useful in solid-phase peptide synthesis (SPPS) where controlled and sequential addition of amino acids is required. The compound is also employed in the preparation of complex peptides and proteins, especially those involving disulfide bond formation, which is critical for the structural stability and biological activity of many peptides. Its application extends to the development of pharmaceuticals, including peptide-based drugs and therapeutic agents.
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