Trimethylacetyl chloride

98%

  • Product Code: 60107
  Alias:    pivaloyl chloride; trimethylacetyl chloride
  CAS:    3282-30-2
Molecular Weight: 120.58 g./mol Molecular Formula: C₅H₉ClO
EC Number: 221-921-6 MDL Number: MFCD00000709
Melting Point: -56 °C Boiling Point: 105-106 °C(lit.)
Density: 0.979 g/mL at 25 °C(lit.) Storage Condition: room temperature, dry
Product Description: Trimethylacetyl chloride is widely used as a reagent in organic synthesis, particularly for introducing the pivaloyl group into molecules. It is commonly employed in the acylation of alcohols, amines, and other nucleophiles to produce esters, amides, and other derivatives. This compound is especially valued in the pharmaceutical industry for synthesizing active pharmaceutical ingredients (APIs) due to its ability to enhance the stability and bioavailability of drug molecules. Additionally, it is utilized in the production of agrochemicals, where it helps create pesticides and herbicides with improved efficacy. In polymer chemistry, trimethylacetyl chloride serves as a modifying agent to tailor the properties of polymers, such as increasing their thermal stability or altering their solubility. Its role in protecting groups during complex multi-step syntheses is also noteworthy, as it helps prevent undesired reactions at specific sites in a molecule.
Product Specification:
Test Specification
REFRACTIVE INDEX N20D 1.409-1.416
PURITYT 97.5-102.5
APPEARANCE Colorless liquid
INFRARED SPECTRUM Conforms to structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
100.000 10-20 days ฿530.00
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500.000 10-20 days ฿1,770.00
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2500.000 10-20 days ฿3,970.00
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10000.000 10-20 days ฿13,400.00
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Trimethylacetyl chloride
Trimethylacetyl chloride is widely used as a reagent in organic synthesis, particularly for introducing the pivaloyl group into molecules. It is commonly employed in the acylation of alcohols, amines, and other nucleophiles to produce esters, amides, and other derivatives. This compound is especially valued in the pharmaceutical industry for synthesizing active pharmaceutical ingredients (APIs) due to its ability to enhance the stability and bioavailability of drug molecules. Additionally, it is utilized in the production of agrochemicals, where it helps create pesticides and herbicides with improved efficacy. In polymer chemistry, trimethylacetyl chloride serves as a modifying agent to tailor the properties of polymers, such as increasing their thermal stability or altering their solubility. Its role in protecting groups during complex multi-step syntheses is also noteworthy, as it helps prevent undesired reactions at specific sites in a molecule.
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