(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether

95%

  • Product Code: 62367
  Alias:    (S)-2-[(bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine
  CAS:    848821-61-4
Molecular Weight: 597.51 g./mol Molecular Formula: C₂₄H₂₃F₁₂NOSi
EC Number: MDL Number: MFCD09750447
Melting Point: 48-56 °C Boiling Point:
Density: Storage Condition: 2~8℃, dry
Product Description: This compound is primarily utilized in asymmetric synthesis and catalysis, particularly in the pharmaceutical industry. It serves as a chiral ligand or catalyst in various enantioselective reactions, such as hydrogenation, alkylation, and cycloaddition processes. Its trifluoromethyl groups enhance its electron-withdrawing properties, making it effective in stabilizing transition states and improving reaction selectivity. Additionally, the trimethylsilyl ether group provides steric protection and enhances solubility in organic solvents, facilitating its use in complex synthetic pathways. Its application is critical in the production of chiral intermediates for active pharmaceutical ingredients (APIs), ensuring high enantiomeric purity in the final products.
Product Specification:
Test Specification
Melting point 48 56?
Purity 95 100%
APPEARANCE WHITE CRYSTAL POWDER
NOTE: This product is low melting point solid,may change state in different environments (solid, liquid or semi-solid)
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
1.000 10-20 days ฿11,860.00
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(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether
This compound is primarily utilized in asymmetric synthesis and catalysis, particularly in the pharmaceutical industry. It serves as a chiral ligand or catalyst in various enantioselective reactions, such as hydrogenation, alkylation, and cycloaddition processes. Its trifluoromethyl groups enhance its electron-withdrawing properties, making it effective in stabilizing transition states and improving reaction selectivity. Additionally, the trimethylsilyl ether group provides steric protection and enhances solubility in organic solvents, facilitating its use in complex synthetic pathways. Its application is critical in the production of chiral intermediates for active pharmaceutical ingredients (APIs), ensuring high enantiomeric purity in the final products.
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