(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether
95%
- Product Code: 62367
Alias:
(S)-2-[(bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine
CAS:
848821-61-4
Molecular Weight: | 597.51 g./mol | Molecular Formula: | C₂₄H₂₃F₁₂NOSi |
---|---|---|---|
EC Number: | MDL Number: | MFCD09750447 | |
Melting Point: | 48-56 °C | Boiling Point: | |
Density: | Storage Condition: | 2~8℃, dry |
Product Description:
This compound is primarily utilized in asymmetric synthesis and catalysis, particularly in the pharmaceutical industry. It serves as a chiral ligand or catalyst in various enantioselective reactions, such as hydrogenation, alkylation, and cycloaddition processes. Its trifluoromethyl groups enhance its electron-withdrawing properties, making it effective in stabilizing transition states and improving reaction selectivity. Additionally, the trimethylsilyl ether group provides steric protection and enhances solubility in organic solvents, facilitating its use in complex synthetic pathways. Its application is critical in the production of chiral intermediates for active pharmaceutical ingredients (APIs), ensuring high enantiomeric purity in the final products.
Product Specification:
Test | Specification |
---|---|
Melting point | 48 56? |
Purity | 95 100% |
APPEARANCE | WHITE CRYSTAL POWDER |
NOTE: | This product is low melting point solid,may change state in different environments (solid, liquid or semi-solid) |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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1.000 | 10-20 days | ฿11,860.00 |
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(S)-α,α-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether
This compound is primarily utilized in asymmetric synthesis and catalysis, particularly in the pharmaceutical industry. It serves as a chiral ligand or catalyst in various enantioselective reactions, such as hydrogenation, alkylation, and cycloaddition processes. Its trifluoromethyl groups enhance its electron-withdrawing properties, making it effective in stabilizing transition states and improving reaction selectivity. Additionally, the trimethylsilyl ether group provides steric protection and enhances solubility in organic solvents, facilitating its use in complex synthetic pathways. Its application is critical in the production of chiral intermediates for active pharmaceutical ingredients (APIs), ensuring high enantiomeric purity in the final products.
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