5-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)pentanamide
95%
- Product Code: 64564
Molecular Weight: | 391.81 g./mol | Molecular Formula: | C₁₈H₁₈ClN₃O₅ |
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EC Number: | MDL Number: | ||
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | 2-8℃ |
Product Description:
This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of targeted cancer therapies. It functions as a key component in proteolysis-targeting chimeras (PROTACs), which are designed to degrade specific disease-causing proteins. By facilitating the ubiquitination and subsequent degradation of these proteins, it plays a crucial role in inhibiting cancer cell proliferation and survival. Additionally, its structure is optimized for binding to E3 ubiquitin ligases, making it a valuable tool in the design of novel therapeutic agents for treating various malignancies. Its application extends to research in understanding protein degradation pathways and developing innovative treatments for other protein-related diseases.
Product Specification:
Test | Specification |
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APPEARANCE | Light yellow solid |
PURITY | 94.5-100 |
NMR | Conforms to Structure |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.100 | 10-20 days | $226.52 |
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0.250 | 10-20 days | $453.04 |
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1.000 | 10-20 days | $887.98 |
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10.000 | 10-20 days | $3,469.73 |
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5-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)pentanamide
This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of targeted cancer therapies. It functions as a key component in proteolysis-targeting chimeras (PROTACs), which are designed to degrade specific disease-causing proteins. By facilitating the ubiquitination and subsequent degradation of these proteins, it plays a crucial role in inhibiting cancer cell proliferation and survival. Additionally, its structure is optimized for binding to E3 ubiquitin ligases, making it a valuable tool in the design of novel therapeutic agents for treating various malignancies. Its application extends to research in understanding protein degradation pathways and developing innovative treatments for other protein-related diseases.
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