4,6-Difluoro-3-iodo-1H-indazole
≥95%
- Product Code: 66332
CAS:
887567-79-5
Molecular Weight: | 280.01 g./mol | Molecular Formula: | C₇H₃F₂IN₂ |
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EC Number: | MDL Number: | MFCD07781823 | |
Melting Point: | Boiling Point: | 355.7±37.0°C at 760 mmHg | |
Density: | Storage Condition: | 2-8°C, protected from light, stored in an inert gas |
Product Description:
4,6-Difluoro-3-iodo-1H-indazole is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of various biologically active compounds. Its structure, featuring both fluorine and iodine substituents, makes it a valuable building block for developing potential pharmaceutical agents, particularly in the design of kinase inhibitors. These inhibitors play a critical role in targeting specific enzymes involved in cellular signaling pathways, which are often implicated in diseases such as cancer and inflammatory disorders. Additionally, the compound's halogenated indazole core is frequently explored in drug discovery programs to optimize the pharmacological properties of new drug candidates, including their potency, selectivity, and metabolic stability. Researchers also leverage its reactivity in cross-coupling reactions to introduce diverse functional groups, further expanding its utility in creating complex molecular architectures for therapeutic applications.
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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0.100 | 10-20 days | $224.39 |
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0.250 | 10-20 days | $448.79 |
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4,6-Difluoro-3-iodo-1H-indazole
4,6-Difluoro-3-iodo-1H-indazole is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of various biologically active compounds. Its structure, featuring both fluorine and iodine substituents, makes it a valuable building block for developing potential pharmaceutical agents, particularly in the design of kinase inhibitors. These inhibitors play a critical role in targeting specific enzymes involved in cellular signaling pathways, which are often implicated in diseases such as cancer and inflammatory disorders. Additionally, the compound's halogenated indazole core is frequently explored in drug discovery programs to optimize the pharmacological properties of new drug candidates, including their potency, selectivity, and metabolic stability. Researchers also leverage its reactivity in cross-coupling reactions to introduce diverse functional groups, further expanding its utility in creating complex molecular architectures for therapeutic applications.
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