(R)-1-(tert-Butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid

97%

  • Product Code: 76158
  CAS:    536747-87-2
Molecular Weight: 251.23 g./mol Molecular Formula: C₁₀H₁₅F₂NO₄
EC Number: MDL Number: MFCD08272893
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry, sealed
Product Description: This compound is primarily used in the pharmaceutical industry as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its structure, featuring a tert-butoxycarbonyl (Boc) protecting group and a difluoropyrrolidine moiety, makes it valuable for the development of protease inhibitors and other drug candidates. The Boc group can be easily removed under mild acidic conditions, allowing for further functionalization of the molecule. The difluoropyrrolidine core is particularly significant in medicinal chemistry due to its ability to enhance the metabolic stability and bioavailability of drug molecules. Additionally, this compound is utilized in peptide synthesis and the creation of peptidomimetics, which are designed to mimic the biological activity of peptides while offering improved stability and efficacy. Its applications extend to research in organic synthesis, where it serves as a building block for the preparation of complex molecules with potential therapeutic properties.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.100 10-20 days ฿3,924.00
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-
0.250 10-20 days ฿6,264.00
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1.000 10-20 days ฿10,305.00
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(R)-1-(tert-Butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid
This compound is primarily used in the pharmaceutical industry as a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its structure, featuring a tert-butoxycarbonyl (Boc) protecting group and a difluoropyrrolidine moiety, makes it valuable for the development of protease inhibitors and other drug candidates. The Boc group can be easily removed under mild acidic conditions, allowing for further functionalization of the molecule. The difluoropyrrolidine core is particularly significant in medicinal chemistry due to its ability to enhance the metabolic stability and bioavailability of drug molecules. Additionally, this compound is utilized in peptide synthesis and the creation of peptidomimetics, which are designed to mimic the biological activity of peptides while offering improved stability and efficacy. Its applications extend to research in organic synthesis, where it serves as a building block for the preparation of complex molecules with potential therapeutic properties.
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