Nutlin-3
≥98%
- Product Code: 77692
CAS:
548472-68-0
| Molecular Weight: | 581.49 g./mol | Molecular Formula: | C₃₀H₃₀Cl₂N₄O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD07784509 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Nutlin-3 is widely used in cancer research as a potent inhibitor of the MDM2-p53 interaction. By blocking this interaction, it activates the p53 tumor suppressor pathway, leading to cell cycle arrest and apoptosis in cancer cells. This makes it a valuable tool for studying p53-dependent mechanisms and developing potential cancer therapies. It is particularly effective in cancers where p53 is wild-type but inhibited by MDM2 overexpression. Additionally, Nutlin-3 is utilized in preclinical studies to evaluate its efficacy in combination with other anticancer agents, enhancing its potential for therapeutic applications.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | ฿10,872.00 |
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Nutlin-3
Nutlin-3 is widely used in cancer research as a potent inhibitor of the MDM2-p53 interaction. By blocking this interaction, it activates the p53 tumor suppressor pathway, leading to cell cycle arrest and apoptosis in cancer cells. This makes it a valuable tool for studying p53-dependent mechanisms and developing potential cancer therapies. It is particularly effective in cancers where p53 is wild-type but inhibited by MDM2 overexpression. Additionally, Nutlin-3 is utilized in preclinical studies to evaluate its efficacy in combination with other anticancer agents, enhancing its potential for therapeutic applications.
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