Semagacestat (LY450139)
≥98%
- Product Code: 77772
CAS:
425386-60-3
| Molecular Weight: | 361.44 g./mol | Molecular Formula: | C₁₉H₂₇N₃O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09970409 | |
| Melting Point: | 208-212°C | Boiling Point: | |
| Density: | Storage Condition: | 2-8°C |
Product Description:
Semagacestat is primarily investigated for its potential in treating Alzheimer's disease. It functions as a gamma-secretase inhibitor, which targets the production of amyloid-beta peptides. These peptides are believed to play a key role in the formation of amyloid plaques, a hallmark of Alzheimer's pathology. By inhibiting gamma-secretase, semagacestat aims to reduce amyloid-beta levels, potentially slowing disease progression. However, clinical trials have shown mixed results, with some studies indicating adverse effects, including worsening cognitive function. Despite these challenges, research continues to explore its therapeutic potential and refine its application in neurodegenerative disorders.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿6,723.00 |
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Semagacestat (LY450139)
Semagacestat is primarily investigated for its potential in treating Alzheimer's disease. It functions as a gamma-secretase inhibitor, which targets the production of amyloid-beta peptides. These peptides are believed to play a key role in the formation of amyloid plaques, a hallmark of Alzheimer's pathology. By inhibiting gamma-secretase, semagacestat aims to reduce amyloid-beta levels, potentially slowing disease progression. However, clinical trials have shown mixed results, with some studies indicating adverse effects, including worsening cognitive function. Despite these challenges, research continues to explore its therapeutic potential and refine its application in neurodegenerative disorders.
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