Triethyl phosphonoacetate
98%
- Product Code: 78952
Alias:
Triethyl phosphonoacetate; Triethyl phosphonoacetate
CAS:
867-13-0
| Molecular Weight: | 224.19 g./mol | Molecular Formula: | C₈H₁₇O₅P |
|---|---|---|---|
| EC Number: | 212-757-6 | MDL Number: | MFCD00009177 |
| Melting Point: | -24°C | Boiling Point: | 142-145 °C9 mm Hg(lit.) |
| Density: | 1.13 g/mL at 25 °C(lit.) | Storage Condition: | 2~8°C |
Product Description:
Triethyl phosphonoacetate is widely used in organic synthesis as a key reagent for the preparation of α,β-unsaturated esters through the Horner-Wadsworth-Emmons (HWE) reaction. This reaction is particularly valuable for forming carbon-carbon double bonds in a highly stereoselective manner, making it essential in the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and natural products. Additionally, it serves as a building block in the production of phosphonate derivatives, which are important in medicinal chemistry for developing enzyme inhibitors and antiviral agents. Its role in cross-coupling reactions also contributes to the creation of advanced materials and fine chemicals.
Product Specification:
| Test | Specification |
|---|---|
| Acid value | 0mgg 2mg/g |
| PurityGC | 98 100% |
| REFRACTIVE INDEX N20D | 1.43-1.432 |
| SPECIFIC GRAVITY 2020C | 1.122-1.125 |
| APPEARANCE | COLORLESS LIQUID |
| INFRARED SPECTRUM | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 25.000 | 10-20 days | ฿290.00 |
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| 100.000 | 10-20 days | ฿410.00 |
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| 500.000 | 10-20 days | ฿1,480.00 |
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| 2500.000 | 10-20 days | ฿6,480.00 |
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Triethyl phosphonoacetate
Triethyl phosphonoacetate is widely used in organic synthesis as a key reagent for the preparation of α,β-unsaturated esters through the Horner-Wadsworth-Emmons (HWE) reaction. This reaction is particularly valuable for forming carbon-carbon double bonds in a highly stereoselective manner, making it essential in the synthesis of complex organic molecules, including pharmaceuticals, agrochemicals, and natural products. Additionally, it serves as a building block in the production of phosphonate derivatives, which are important in medicinal chemistry for developing enzyme inhibitors and antiviral agents. Its role in cross-coupling reactions also contributes to the creation of advanced materials and fine chemicals.
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