1-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-(propan-2-yl)urea

95%

  • Product Code: 80023
  CAS:    2246769-29-7
Molecular Weight: 322.1828 g./mol Molecular Formula: C₁₆H₂₄BFN₂O₃
EC Number: MDL Number: MFCD32206475
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of kinase inhibitors. Its structure, featuring a dioxaborolane group, makes it a valuable intermediate in Suzuki-Miyaura cross-coupling reactions, which are widely employed in the synthesis of complex organic molecules, including pharmaceuticals. The fluorine atom enhances its binding affinity to target proteins, while the urea moiety contributes to its ability to form hydrogen bonds, improving its interaction with biological targets. This chemical is often explored in the design of drugs targeting cancer, inflammation, and other diseases where kinase modulation is therapeutic. Its application in drug discovery is driven by its potential to improve selectivity and efficacy in inhibiting specific kinases.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.025 10-20 days $110.17
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0.100 10-20 days $329.97
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1-[2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-(propan-2-yl)urea
This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of kinase inhibitors. Its structure, featuring a dioxaborolane group, makes it a valuable intermediate in Suzuki-Miyaura cross-coupling reactions, which are widely employed in the synthesis of complex organic molecules, including pharmaceuticals. The fluorine atom enhances its binding affinity to target proteins, while the urea moiety contributes to its ability to form hydrogen bonds, improving its interaction with biological targets. This chemical is often explored in the design of drugs targeting cancer, inflammation, and other diseases where kinase modulation is therapeutic. Its application in drug discovery is driven by its potential to improve selectivity and efficacy in inhibiting specific kinases.
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