1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

95%

  • Product Code: 82422
  CAS:    40733-26-4
Molecular Weight: 470.75 g./mol Molecular Formula: C₂₂H₄₂N₂O₅Si₂
EC Number: MDL Number: MFCD01631042
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C
Product Description: This compound is primarily used in the synthesis of nucleoside analogs, which are crucial in the development of antiviral and anticancer drugs. Its structure, featuring protected hydroxyl groups, allows for precise manipulation in organic synthesis, particularly in the construction of complex nucleotide frameworks. The tert-butyldimethylsilyl (TBDMS) groups serve as protective moieties, ensuring selective reactivity during multi-step synthetic processes. This chemical is often employed in the preparation of modified nucleosides that target viral polymerases or cellular enzymes, making it valuable in medicinal chemistry research. Additionally, it plays a role in the study of nucleic acid interactions and the development of therapeutic agents for diseases like HIV, hepatitis, and certain cancers.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.100 10-20 days ฿14,040.00
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0.250 10-20 days ฿23,400.00
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1.000 10-20 days ฿46,800.00
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1-((2R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
This compound is primarily used in the synthesis of nucleoside analogs, which are crucial in the development of antiviral and anticancer drugs. Its structure, featuring protected hydroxyl groups, allows for precise manipulation in organic synthesis, particularly in the construction of complex nucleotide frameworks. The tert-butyldimethylsilyl (TBDMS) groups serve as protective moieties, ensuring selective reactivity during multi-step synthetic processes. This chemical is often employed in the preparation of modified nucleosides that target viral polymerases or cellular enzymes, making it valuable in medicinal chemistry research. Additionally, it plays a role in the study of nucleic acid interactions and the development of therapeutic agents for diseases like HIV, hepatitis, and certain cancers.
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