4-Cyano-4-(phenylcarbonothioylthio)pentanoic acid N-succinimidyl ester
- Product Code: 83942
Alias:
4-cyano-4-[(phenylthiomethyl)thio]-2,5-dioxo-1-pyrrolidinyl valeric acid, 4-cyano-4-(phenylthiomethyl) Thio)pentanoic acid N-hydroxysuccinimidyl ester, NHS protected RAFT, RAFT polymerizer
CAS:
864066-74-0
| Molecular Weight: | 376.45 g./mol | Molecular Formula: | C₁₇H₁₆N₂O₄S₂ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | 175-185 °C | Boiling Point: | |
| Density: | Storage Condition: | 2-8°C |
Product Description:
This compound is widely used in reversible addition-fragmentation chain transfer (RAFT) polymerization, a technique for producing polymers with controlled molecular weights and narrow dispersities. It acts as a RAFT agent, enabling precise control over the polymerization process, which is essential for creating tailored polymers for specific applications.
In bioconjugation, it serves as a linker to attach functional groups or biomolecules to polymers or surfaces. Its succinimidyl ester group reacts with primary amines, making it valuable for modifying proteins, peptides, or other amine-containing molecules. This is particularly useful in drug delivery systems, where it helps create polymer-drug conjugates for targeted therapy.
Additionally, it is employed in surface modification to introduce specific functionalities onto materials, enhancing their compatibility with biological systems or improving their performance in applications like biosensors or coatings. Its versatility in controlled polymerization and bioconjugation makes it a key tool in materials science and biotechnology.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Red to Very Dark Red and Pink Powder or Crystals |
| CARBON | 47.7 % 60.7 % |
| NITROGEN | 6.5 % 8.4 % |
| Infrared spectrum | Conforms to Structure |
| SULFUR | 14.9 % 19.1 % |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | £137.51 |
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| 0.250 | 10-20 days | £293.57 |
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4-Cyano-4-(phenylcarbonothioylthio)pentanoic acid N-succinimidyl ester
This compound is widely used in reversible addition-fragmentation chain transfer (RAFT) polymerization, a technique for producing polymers with controlled molecular weights and narrow dispersities. It acts as a RAFT agent, enabling precise control over the polymerization process, which is essential for creating tailored polymers for specific applications.
In bioconjugation, it serves as a linker to attach functional groups or biomolecules to polymers or surfaces. Its succinimidyl ester group reacts with primary amines, making it valuable for modifying proteins, peptides, or other amine-containing molecules. This is particularly useful in drug delivery systems, where it helps create polymer-drug conjugates for targeted therapy.
Additionally, it is employed in surface modification to introduce specific functionalities onto materials, enhancing their compatibility with biological systems or improving their performance in applications like biosensors or coatings. Its versatility in controlled polymerization and bioconjugation makes it a key tool in materials science and biotechnology.
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